Results 181 to 190 of about 94,252 (292)

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

Sex differences in G protein-coupled estrogen receptor-mediated mechanisms in preclinical models of anxiety and fear. [PDF]

Front Behav Neurosci
Tran AS, Maeng LY.
europepmc   +1 more source

Stimulatory Anticancer Effect of Resveratrol Mediated by G Protein-Coupled Estrogen Receptor in Colorectal Cancer. [PDF]

Biomol Ther (Seoul), 2023
Kim N, Kwon J, Shin US, Jung J.
europepmc   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

G protein-coupled Estrogen Receptor Activation Exerts Protective Effects via Modulating Brain and Gut NLRP3 Inflammasome in Parkinson's Disease. [PDF]

Exp Neurobiol
Liang Y, Zhou L, Liu H, Huang X, Li Y, Li X, Huang S.   +6 more
europepmc   +1 more source

Connecting G protein-coupled estrogen receptor biomolecular mechanisms with the pathophysiology of preeclampsia: a review. [PDF]

Reprod Biol Endocrinol, 2023
Alencar AKN, Swan KF, Pridjian G, Lindsey SH, Bayer CL.   +4 more
europepmc   +1 more source

Estrogens and the G protein-coupled estrogen receptor in prostate cancer: angels or demons?

, 2023
Prostate cancer (PCa) is the second most frequent type of cancer among men, with an increasing incidence worldwide. PCa is highly regulated by hormones, with androgens playing a crucial role in its development and progression. However, also estrogens are accepted to influence PCa.
openaire   +1 more source

Integrative Assessment of Desmostachya bipinnata (L.) Root Extract: Anti‐Inflammatory and Antinociceptive Effects Supported by Molecular Docking and Network Pharmacology

Flavour and Fragrance Journal, EarlyView.
The ethanolic root extract of Desmostachya bipinnata exhibited significant anti‐inflammatory and antinociceptive activities in in vitro, in vivo and in silico models, revealing bioactive compounds capable of modulating key inflammatory targets and supporting the plant's traditional therapeutic potential.
Muhammad Hussnain Siddique, Muhammad Muzammil Nazir, Saima Muzammil, Iqra Farzeen, Shafaq Latif, Asma Ashraf, Jorddy Neves Cruz   +6 more
wiley   +1 more source

Association Between Serum G Protein-Coupled Estrogen Receptor and the Peripheral Blood Balance of T-Helper/New Effector T-Cells in Patients With Hashimoto's Thyroiditis. [PDF]

Int J Endocrinol
Zang X, Chen W, Liu R, Lin Y, Liu X, Geng H, Liang J.   +6 more
europepmc   +1 more source

G Protein-Coupled Estrogen Receptor GPER: Molecular Pharmacology and Therapeutic Applications. [PDF]

Annu Rev Pharmacol Toxicol, 2023
Arterburn JB, Prossnitz ER.
europepmc   +1 more source