Results 91 to 100 of about 16,799,603 (206)

G-Protein-Coupled Estrogen Receptor (GPER) in Inflammatory Myopathies

Neurology International
Background/Objectives: Given the multifaceted role of estrogen hormones in skeletal muscle pathophysiology and their well-established immunomodulatory properties, this study aimed to characterize the expression of the G-protein-coupled estrogen receptor (
Delia Righi, Diego Lopergolo, Nila Volpi, Daniela Franci, Paola Lorenzoni, Margherita Aglianò, Gianna Berti, Carlo Manco, Nicola De Stefano, Federica Ginanneschi   +9 more
doaj   +1 more source

The complex roles of μ-opioid receptor phosphorylation: A key determinant in receptor signaling and regulation

, 2015
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics. This Commentary focuses on two articles in the October 2015 issue of Molecular Pharmacology that investigate the role of μ-opioid receptor phosphorylation in ...
Canals, Meritxell
core   +1 more source

Editorial: G Protein-Coupled Receptor Kinases (GRKs) and β-Arrestins: New Insights Into Disease Regulators

Frontiers in Pharmacology, 2020
Yuichi Hattori, Martin C. Michel
doaj   +1 more source

G protein coupled receptors.

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as post-translation ...
Conn, P. Michael.
core  

Cannabinoid-Driven Rewiring of GPCR and Ion Channel Signaling in Lung Cancer

Biomedicines
Lung cancer remains the leading cause of cancer-related mortality worldwide, with non-small cell lung cancer accounting for the majority of cases and exhibiting persistent challenges related to therapy resistance and metastatic progression.
Didik Setyo Heriyanto, Fahrul Nurkolis, Jinwon Choi, Sohyun Park, Min Choi, Raymond Rubianto Tjandrawinata, Amama Rani, Moon Nyeo Park, Min-Jin Kwak, Bum Sang Shim, Bonglee Kim   +10 more
doaj   +1 more source

A systems and molecular analysis of G protein-mediated signalling [PDF]

The ability of cells to respond correctly to signals from their microenvironment is an essential prerequisite of life. Many external signals are detected through G protein-coupled receptor (GPCR) signalling pathways, which control all aspects of ...
Croft, Wayne D.
core  

Molecular dynamics study of melatonin binding to homology modelled Mel1a G-protein coupled receptor [PDF]

, 2018
The Mel1a G-coupled Protein receptor (GPCR) was modelled using the I-Tasser online web service. All-atom molecular dynamics was used to improve the structure.
Carey, D.
core  

The molecular basis of V2 vasopressin receptor-G Protein coupling selectivity [PDF]

, 2003
G­Protein­gekoppelte Rezeptoren (GPCRs) stellen eine der größten in der Natur vorkommenden Proteinfamilien dar (Watson and Arkinstall, 1994). GPCRs sind plasmamembranständige Proteine, die mit heterotrimären G­Proteinen interagieren und eine Vielzahl an ...
Erlenbach, Isolde
core  

Biochemische und funktionelle Charakterisierung zellfrei exprimierter G-Protein-gekoppelter Rezeptoren des humanen Endothelin-Systems [PDF]

, 2011
G-protein coupled receptors (GPCRs) are the key players in signal perception and transduction and one of the currently most important class of drug targets.
Junge, Friederike Alessandra
core  

Systematic Assessment of Human CCR7 Signalling Using NanoBRET Biosensors Points towards the Importance of the Cellular Context

Biosensors
The human CC chemokine receptor 7 (CCR7) is activated by two natural ligands, CC chemokine ligand 19 (CCL19) and 21 (CCL21). The CCL19-CCL21-CCR7 axis has been extensively studied in vitro, but there is still debate over whether CCL21 is an overall ...
Nathan Vanalken, Katrijn Boon, Martyna Szpakowska, Andy Chevigné, Dominique Schols, Tom Van Loy   +5 more
doaj   +1 more source