Results 291 to 300 of about 1,156,973 (433)

Role of G-protein βγ subunits in the augmentation of P2Y2 (P2U) receptor-stimulated responses by neuropeptide Y Y1 Gi/o-coupled receptors [PDF]

, 1997
A. Lisa SELBIE, Natalie King, John M. Dickenson, Stephen J. Hill   +3 more
openalex   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Potential role of G protein‑coupled receptor 124 in cardiovascular and cerebrovascular disease (Review). [PDF]

Exp Ther Med
Lin WY, Dong YL, Lin Y, Sunchuri D, Guo ZL.   +4 more
europepmc   +1 more source

Deletion of the R78 G Protein-Coupled Receptor Gene from Rat Cytomegalovirus Results in an Attenuated, Syncytium-Inducing Mutant Strain

, 1999
Patrick S. Beisser, Gert Grauls, Cathrien A. Bruggeman, Cornelis Vink   +3 more
openalex   +1 more source

Altered Activity of Palmitoylation-deficient and Isoprenylated Forms of the G Protein-coupled Receptor Kinase GRK6 [PDF]

, 1997
R Loudon, Jeffrey Benovic
openalex   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

G-Protein-Coupled Receptor 84 Aggravates Early Brain Injury via Microglial NLRP3-ASC Inflammasome After Subarachnoid Hemorrhage. [PDF]

Brain Behav
Jiang K, Zou Y, Song Y, Zhou L, Zhang B, Zhou X, Zhang X.   +6 more
europepmc   +1 more source

A human gene encodes a putative G protein-coupled receptor highly expressed in the central nervous system [PDF]

, 1998
Patrick J. Donohue, Hagit Shapira, Samuel A. Mantey, Lori L. Hampton, Robert T. Jensen, James F. Battey   +5 more
openalex   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Structures of G-protein coupled receptor HCAR1 in complex with Gi1 protein reveal the mechanistic basis for ligand recognition and agonist selectivity. [PDF]

PLoS Biol
Pan X, Ye F, Ning P, Yu Y, Zhang Z, Wang J, Chen G, Wu Z, Qiu C, Li J, Chen B, Zhu L, Qian C, Gong K, Du Y.   +14 more
europepmc   +1 more source