Results 161 to 170 of about 396,098 (353)

Delineation of G Protein-Coupled Receptor Kinase Phosphorylation Sites within the D₁ Dopamine Receptor and Their Roles in Modulating β-Arrestin Binding and Activation. [PDF]

Int J Mol Sci, 2023
Moritz AE, Madaras NS, Rankin ML, Inbody LR, Sibley DR.   +4 more
europepmc   +1 more source

Identification by polymerase chain reaction of the G protein-coupled receptor kinases expressed in the mouse gonadotropic alpha T3-1 cell line. [PDF]

, 1996
Jimmy D. Neill, Lois C. Musgrove, Jeffrey C. Sellers, L. Wayne Duck   +3 more
openalex   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

G protein-coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1. [PDF]

Blood Adv, 2022
Downes K, Zhao X, Gleadall NS, McKinney H, Kempster C, Batista J, Thomas PL, Cooper M, Michael JV, Kreuzhuber R, Wedderburn K, Waller K, Varney B, Verdier H, Kriek N, Ashford SE, Stirrups KE, Dunster JL, McKenzie SE, Ouwehand WH, Gibbins JM, Yang J, Astle WJ, Ma P.   +23 more
europepmc   +1 more source

B014 Ischemic inactivation of G protein-coupled receptor kinase and altered desensitization of canine cardiac $beta;-adrenergic receptors [PDF]

, 1998
Minghui Zhang
openalex   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

G protein-coupled receptor kinase 6 (GRK6) regulates insulin processing and secretion via effects on proinsulin conversion to insulin. [PDF]

J Biol Chem, 2022
Varney MJ, Steyaert W, Coucke PJ, Delanghe JR, Uehling DE, Joseph B, Marcellus R, Al-Awar R, Benovic JL.   +8 more
europepmc   +1 more source

Molecular modeling of G-protein coupled receptor kinase 2: Docking and biochemical evaluation of inhibitors [PDF]

, 2000
Matthias U. Kassack, Petra Högger, Daniel A. Gschwend, Kimihiko Kameyama, Tatsuya Haga, Richard C. Graul, Wolfgang Sadée   +6 more
openalex   +1 more source

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

FEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis   +6 more
wiley   +1 more source

Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors [PDF]

, 2000
Kristen L. Pierce, Stuart Maudsley, Yehia Daaka, Louis M. Luttrell, Robert J. Lefkowitz   +4 more
openalex   +1 more source