Results 241 to 250 of about 426,123 (306)

G‐protein coupled receptor kinase 5 mediates lipopolysaccharide‐induced NFκB activation in primary macrophages and modulates inflammation in vivo in mice [PDF]

, 2010
Sonika Patial, Shipra Shahi, Yogesh Saini, Taehyung C. Lee, Nandakumar Packiriswamy, Daniel M. Appledorn, John J. LaPres, Andrea Amalfitano, Narayanan Parameswaran   +8 more
openalex   +1 more source

Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior

Advanced Healthcare Materials, EarlyView.
Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley   +1 more source

Characterization of a hyperphosphorylated variant of G protein-coupled receptor kinase 5 expressed in E. coli. [PDF]

Protein Expr Purif, 2020
Beyett TS, Chen Q, Labudde EJ, Krampen J, Sharma PV, Tesmer JJG.   +5 more
europepmc   +1 more source

At the Pointy End of Mechanobiology: AFM for Transient Biomechanical Analysis

Advanced Healthcare Materials, EarlyView.
Stem cell mechanosensitivity governs lineage commitment through mechanotransduction, but capturing these transient changes in living cells remains challenging. Advanced atomic force microscopy enables high‐resolution analysis of mechanical properties, real‐time protein distribution, and gene expression, offering fresh insights into cell‐environment ...
Kaiwen Zhang, Chayla L. Reeves, Mehrnoosh Moghaddar, Kate E. Fox, Aaron Elbourne, Amy Gelmi   +5 more
wiley   +1 more source

The diverse roles of G protein-coupled receptor kinase 2 (GRK2): a focus on regulation of receptor tyrosine kinases (RTKs).

, 2014

openalex   +1 more source

High Efficiency Method for Gene Transfer in Normal Pituitary Gonadotropes: Adenoviral-Mediated Expression of G Protein-Coupled Receptor Kinase 2 Suppresses Luteinizing Hormone Secretion [PDF]

, 1999
J. D. Neill
openalex   +1 more source

Controlling Intestinal Organoid Polarity using Synthetic Dynamic Hydrogels Decorated with Laminin‐Derived IKVAV Peptides

Advanced Healthcare Materials, EarlyView.
Design rules are presented to control intestinal organoid polarity in fully synthetic hydrogels. The laminin‐derived IKVAV sequence is crucial to obtain correct intestinal organoid polarity. Increasing hydrogel dynamics further supports the growth of correctly polarized intestinal organoids, while a bulk level of stiffness (G’ ≈ 0.7 kPa) is crucial to ...
Laura Rijns, Joost A. P. M. Wijnakker, Victor A. Veenbrink, Riccardo Bellan, Fenna W. B. Craenmehr, Simone I. S. Hendrikse, Johnick F. van Sprang, Wim de Lau, E. W. Meijer, Hans Clevers, Patricia Y. W. Dankers   +10 more
wiley   +1 more source

AKAPs (A-kinase anchoring proteins) and molecules that compose their G-protein-coupled receptor signalling complexes [PDF]

, 2004
Craig C. Malbon, Jiangchuan Tao, Hsien‐yu Wang   +2 more
openalex   +1 more source

Borate‐Ion‐Stimulated Macrophages Promote Osteogenic Differentiation of Mesenchymal Stem Cells

Advanced Healthcare Materials, EarlyView.
The immune responses of mouse macrophages stimulated by borate ions promote the osteogenic differentiation and mineralization of mouse bone marrow–derived mesenchymal stem cells in an ion‐dose‐dependent manner by providing cytokines, including BMP‐2.
Kazumasa Ikedo, Hiroki Hatakeyama, Sayaka Oguri, Akiko Obata, Toshihiro Kasuga   +4 more
wiley   +1 more source

G-Protein-Coupled Receptor Kinase-Interacting Protein 1 (GIT1) Promotes Head and Neck Squamous Cell Carcinoma Metastases via Activating the PI3K/AKT/mTOR Signal Pathway.

Comput Math Methods Med, 2022
Xu R, Xu R, Wang Y, Wang W, Jiang L, Gong S.   +5 more
europepmc   +1 more source