Results 41 to 50 of about 536,609 (348)
Multiple regulatory domains on the Byr2 protein kinase [PDF]
, 1997 Byr2 protein kinase, a homolog of mammalian mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEKK) and Saccharomyces cerevisiae STE11, is required for pheromone-induced sexual differentiation in the fission yeast ...
Tu, H. +3 more
core +1 more source
G Protein-Coupled Receptor Kinase 4 [PDF]
Hypertension, 2015 The kidney plays an important role in the long-term control of blood pressure and is the major organ involved in the regulation of sodium homeostasis.1 The inappropriate sodium retention in hypertension results from enhanced renal sodium transport per se or a failure to respond appropriately to signals that decrease renal sodium transport in the face ...
Jian, Yang +4 more
openaire +2 more sources
Homologous and Heterologous Phosphorylations of Human Histamine H1 Receptor in Intact Cells
Journal of Pharmacological Sciences, 2004 Homologous and heterologous phosphorylations of histamine H1 receptor (H1R) in intact cells were investigated using Chinese hamster ovary cells stably co-expressing c-myctagged human histamine H1 and muscarinic M3 receptors. Increase in histamine-induced
Katsuhiro Miyoshi +3 more
doaj +1 more source
High-fat diet induces protein kinase A and G-protein receptor kinase phosphorylation of β2 -adrenergic receptor and impairs cardiac adrenergic reserve in animal hearts. [PDF]
, 2017 Key pointsPatients with diabetes show a blunted cardiac inotropic response to β-adrenergic stimulation despite normal cardiac contractile reserve. Acute insulin stimulation impairs β-adrenergically induced contractile function in isolated cardiomyocytes ...
Chiamvimonvat, Nipavan +8 more
core +2 more sources
Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes. [PDF]
, 2015 Protease-activated receptor 1 (PAR1) is a G protein-coupled receptor (GPCR) for thrombin and promotes inflammatory responses through multiple pathways including p38 mitogen-activated protein kinase signaling.
Aguilar, Berenice +7 more
core +2 more sources
G protein-coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor-promoted centrosomal separation. [PDF]
, 2013 G protein-coupled receptor kinases (GRKs) play a central role in regulating receptor signaling, but recent studies suggest a broader role in modulating normal cellular functions.
Benovic, Jeffrey L +4 more
core +2 more sources
Frontiers in Bioscience-Landmark, 2020 Chemokines are small regulatory proteins that play a crucial role in the coordinated migration of cell populations to the site of infection/inflammation by binding to their cognate receptors.
Deepak Kumar Tripathi +1 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2022 Chlorobisphenol A (ClxBPA) is a kind of novel estrogenic compounds. The present study aims to investigate the effects of three ClxBPA compounds on the kisspeptin/G protein-coupled receptor 54 (GPR54, also named KissR1)-gonadotropin-releasing hormone ...
Bingli Lei +5 more
doaj +1 more source
Characterization of the G Protein-coupled Receptor Kinase GRK4
Journal of Biological Chemistry, 1996 A novel human G protein-coupled receptor kinase was recently identified by positional cloning in the search for the Huntington's disease locus (Ambrose, C., James, M., Barnes, G., Lin, C., Bates, G., Altherr, M., Duyao, M., Groot, N., Church, D., Wasmuth,
R. T. Premont +8 more
semanticscholar +1 more source
Ligand-induced dynamics of heterotrimeric G protein-coupled receptor-like kinase complexes.
PLoS ONE, 2017 BackgroundArabidopsis, 7-transmembrane Regulator of G signaling protein 1 (AtRGS1) modulates canonical G protein signaling by promoting the inactive state of heterotrimeric G protein complex on the plasma membrane.
Meral Tunc-Ozdemir, Alan M Jones
doaj +1 more source