Results 151 to 160 of about 500,528 (216)
Autoantibodies Targeting G-Protein-Coupled Receptors and RAS-Related Molecules in Post-Acute COVID Vaccination Syndrome: A Retrospective Case Series Study. [PDF]
BiomedicinesMantovani M +6 more
europepmc +1 more source
G protein-coupled receptors and traditional Chinese medicine: new thinks for the development of traditional Chinese medicine. [PDF]
Chin MedZhang T, An W, You S, Chen S, Zhang S.
europepmc +1 more source
Growth factor-dependent phosphorylation of Gαi shapes canonical signaling by G protein-coupled receptors. [PDF]
Sci SignalRoy S +5 more
europepmc +1 more source
Mechanosensitive adhesion G protein-coupled receptors: Insights from health and disease. [PDF]
Genes DisSun S, Wang W.
europepmc +1 more source
G-protein-coupled receptors and cancer [PDF]
Nature Reviews Cancer, 2007 G-protein-coupled receptors (GPCRs), the largest family of cell-surface molecules involved in signal transmission, have recently emerged as crucial players in tumour growth and metastasis. Malignant cells often hijack the normal physiological functions of GPCRs to survive, proliferate autonomously, evade the immune system, increase their blood supply ...
R. Dorsam, J. Gutkind
semanticscholar +3 more sources
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This is not a G protein-coupled receptor
Trends in Pharmacological Sciences, 1993On his canvas entitled 'La trahison des Images' ('The Perfidy of Images'), René Magritte painted a tobacco pipe in a very realistic manner and added the words: 'Ceci n'est pas une pipe' ('This is not a pipe'). In similar style, it is of prime importance to state that the first three-dimensional (3D) models of G protein-coupled receptors (GPCRs) that ...
Marcel Hibert +3 more
openaire +2 more sources
Molecular Pharmacology, 2003
The superfamily of G-protein-coupled receptors (GPCRs) is very diverse in structure and function and its members are among the most pursued targets for drug development.
R. Fredriksson +3 more
semanticscholar +1 more source
The superfamily of G-protein-coupled receptors (GPCRs) is very diverse in structure and function and its members are among the most pursued targets for drug development.
R. Fredriksson +3 more
semanticscholar +1 more source
2008
G-Protein-coupled receptors mediate many of the hypnotic and analgesic actions of the drugs employed in anesthesia. Notably, opioid agonists represent the most successful and efficacious class of analgesic agents employed over the last century. Also, major clinical advances have been made by the study of alpha(2) adrenoceptor agonists, which possess ...
R D, Sanders, D, Brian, M, Maze
openaire +2 more sources
G-Protein-coupled receptors mediate many of the hypnotic and analgesic actions of the drugs employed in anesthesia. Notably, opioid agonists represent the most successful and efficacious class of analgesic agents employed over the last century. Also, major clinical advances have been made by the study of alpha(2) adrenoceptor agonists, which possess ...
R D, Sanders, D, Brian, M, Maze
openaire +2 more sources
Current Biology, 1992
The diversity of the G protein-coupled receptor superfamily is now being realised with the molecular cloning of DNA encoding many new receptors and receptor subfamilies. The existing pharmacological definitions of receptor subtypes have been extended dramatically with identification of additional subtypes at the molecular level.
John Shine, Tiina P. Iismaa
openaire +3 more sources
The diversity of the G protein-coupled receptor superfamily is now being realised with the molecular cloning of DNA encoding many new receptors and receptor subfamilies. The existing pharmacological definitions of receptor subtypes have been extended dramatically with identification of additional subtypes at the molecular level.
John Shine, Tiina P. Iismaa
openaire +3 more sources