Results 201 to 210 of about 818,382 (379)

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

Neuron, 2009
G. M. Alexander, Sarah C. Rogan, Atheir I. Abbas, Blaine N. Armbruster, Ying Pei, John A. Allen, R. Nonneman, J. Hartmann, S. Moy, M. Nicolelis, J. McNamara, B. Roth   +11 more
semanticscholar   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Identifying the biomarkers associated with G protein-coupled receptors of parkinson's disease. [PDF]

Sci Rep
Yang H, Wu X, Yun Y, Bao Z, Peng D, Wu Z, Zhang W.   +6 more
europepmc   +1 more source

Biased Agonism of G Protein-Coupled Receptors: A Potential Therapeutic Strategy of Cardiovascular Diseases

, 2016
Yun Hak Kim, Sae Ock Oh
openalex   +1 more source

Chaperoning G Protein-Coupled Receptors: From Cell Biology to Therapeutics [PDF]

, 2014
Ya‐Xiong Tao, P. Michael Conn
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

G Protein-Coupled Receptors in Irritable Bowel Syndrome: Mechanisms and Therapeutic Opportunities. [PDF]

Int J Mol Sci
Zhu Z, Liu Z, He Y, He X, Zheng W, Jiang M.   +5 more
europepmc   +1 more source

Modeling and Docking the Endothelin G-Protein-Coupled Receptor [PDF]

, 2000
Andrew Orry, B.A. Wallace
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

G Protein-Coupled Receptors in Cerebrovascular Diseases: Signaling Mechanisms and Therapeutic Opportunities. [PDF]

Int J Mol Sci
Gu Q, Yao J, Sheng J, Liu D.
europepmc   +1 more source