Results 261 to 270 of about 776,363 (406)

A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Loss‐of‐function mutations in the scaffold subunit of protein phosphatase 2A (PP2A), PPP2R1A, sensitize ovarian clear cell carcinoma to immune checkpoint blockade (ICB) by enhancing the interferon gamma response and promoting antitumor immune cell infiltration.
Matheus Henrique Dias, René Bernards
wiley   +1 more source

Lipid-mediated Regulation of G Protein-coupled Receptor Kinases 2 and 3 [PDF]

open access: hybrid, 1995
Shubhik DebBurman   +5 more
openalex   +1 more source

Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors

open access: yesNature, 2004
Weihai He   +8 more
semanticscholar   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

G proteins of the Gq family couple the H2 histamine receptor to phospholipase C. [PDF]

open access: bronze, 1996
Bernhard Kühn   +4 more
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2015
Hannah M. Stoveken   +3 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy