Results 261 to 270 of about 818,382 (379)

Constitutively active orphan G protein-coupled receptors through the lenses of cryo-electron microscopy. [PDF]

J Biol Chem
Argerich J, Muñoz-Reyes D, Val-García ID, García-Nafría J.   +3 more
europepmc   +1 more source

The Chain Length Dependence of Helix Formation of the Second Transmembrane Domain of a G Protein-coupled Receptor ofSaccharomyces cerevisiae

, 2002
Fa‐Xiang Ding, David Schreiber, Nathan C. VerBerkmoes, Jeffrey M. Becker, Fred Naider   +4 more
openalex   +1 more source

Activation of Platelet Function Through G Protein–Coupled Receptors

Circulation Research, 2006
S. Offermanns
semanticscholar   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Insights into the structural dynamics of the secretin family (class B1) G protein-coupled receptors. [PDF]

J Biol Chem
Liu T, Naidoo NR, Agyemang E, Lamichhane R.   +3 more
europepmc   +1 more source

The Discovery of a New Non-Bile Acid Modulator of Takeda G Protein-Coupled Receptor 5: An Integrated Computational Approach

Rudy Salam
openalex   +1 more source

The G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) facilitates tumor development by serving as an extracellular pH sensor [PDF]

, 2010
Yuichiro Ihara, Yasuyuki Kihara, Fumie Hamano, K. Yanagida, Yasuyuki Morishita, Akiko Kunita, Takao Yamori, Masashi Fukayama, Hiroyuki Aburatani, Takao Shimizu, Satoshi Ishii   +10 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

G protein-coupled receptors: pivotal hubs in gastric cancer malignancy-from multidimensional crosstalk to precision therapeutics. [PDF]

J Transl Med
Qin R, Fan X, Huang Y, Duan Y, Wang H.
europepmc   +1 more source

Threonine 180 Is Required for G-protein-coupled Receptor Kinase 3- and β-Arrestin 2-mediated Desensitization of the μ-Opioid Receptor in Xenopus Oocytes

, 2001
Jeremy Celver, Janet Lowe, Abraham Kovoor, Vsevolod V. Gurevich, Charles Chavkin   +4 more
openalex   +1 more source