Results 41 to 50 of about 21,426,917 (362)
MAPKs in development: insights from Dictyostelium signaling pathways
Biomolecular Concepts, 2011 Mitogen activated protein kinases (MAPKs) play important roles in the development of eukaryotic organisms through the regulation of signal transduction pathways stimulated by external signals.
Hadwiger Jeffrey A., Nguyen Hoai-Nghia
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Multi-Omics Analysis of Multiple Glucose-Sensing Receptor Systems in Yeast
Biomolecules, 2022 The yeast Saccharomyces cerevisiae has long been used to produce alcohol from glucose and other sugars. While much is known about glucose metabolism, relatively little is known about the receptors and signaling pathways that indicate glucose availability.
Shuang Li +7 more
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Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes
Science, 2019 Choosing a partner G protein–coupled receptors (GPCRs) bind ligands outside the cell and trigger events inside the cell by selectively binding and activating specific G proteins. The selectivity occurs even among highly related GPCRs.
S. Maeda +4 more
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Electrospun Nanofibers and their Application in Tissue Repair and Engineering
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020 Introduction: Tissue engineering is the repair and replacement of damaged tissues and requires a combination of cells, growth factor and porous scaffolds.
Sareh Arjmand +3 more
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Scientific Reports, 2018 CarD is an essential global transcription regulator from Mycobacterium tuberculosis (Mtb) that binds RNA polymerase and activates transcription by stabilizing the transcription initiation complex.
Gundeep Kaur +5 more
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Heterotrimeric G-Protein Signalers and RGSs in Aspergillus fumigatus
Pathogens, 2020 The heterotrimeric G-protein (G-protein) signaling pathway is one of the most important signaling pathways that transmit external signals into the inside of the cell, triggering appropriate biological responses. The external signals are sensed by various
Hee-Soo Park +3 more
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Mini G protein probes for active G protein–coupled receptors (GPCRs) in live cells
Journal of Biological Chemistry, 2018 G protein–coupled receptors (GPCRs) are key signaling proteins that regulate nearly every aspect of cell function. Studies of GPCRs have benefited greatly from the development of molecular tools to monitor receptor activation and downstream signaling ...
Qingwen Wan +6 more
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The Disruption of a Gα Subunit Sheds New Light on the Pathogenicity of Stagonospora nodorum on Wheat
Molecular Plant-Microbe Interactions, 2004 Gna1, a gene encoding a Gα subunit, a key component of signal transduction pathways, has been cloned and characterized in the wheat pathogen Stagonospora nodorum.
Peter S. Solomon +4 more
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A G-protein pathway determines grain size in rice
Nature Communications, 2018 Manipulating grain size is an effective strategy for increasing cereal yields. Here we identify a pathway composed of five subunits of the heterotrimeric G proteins that regulate grain length in rice.
Shengyuan Sun +7 more
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DEER Analysis of GPCR Conformational Heterogeneity
Biomolecules, 2021 G protein-coupled receptors (GPCRs) represent a large class of transmembrane helical proteins which are involved in numerous physiological signaling pathways and therefore represent crucial pharmacological targets.
Matthias Elgeti, Wayne L. Hubbell
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