Results 261 to 270 of about 171,723 (359)

Massive Activation of GABA_A Receptors: Rundown, Ionic and Neurodegenerative Consequences. [PDF]

Biomolecules
Menzikov SA, Zaichenko DM, Moskovtsev AA, Morozov SG, Kubatiev AA.   +4 more
europepmc   +1 more source

Acute sleep deprivation preconditions the heart against ischemia/ reperfusion injury: the role of central GABA-A receptors. [PDF]

Iran J Basic Med Sci, 2017
Parsa H, Imani A, Faghihi M, Riahi E, Badavi M, Shakoori A, Rastegar T, Aghajani M, Rajani SF.   +8 more
europepmc   +1 more source

Neuroprotective Efficacy of Microwave‐Assisted Synthetized 2‐(5‐Cyclopropyl‐6‐Thioxo‐1,3,5‐Thiadiazinan‐3‐Yl) Acetic Acid in Mitigating Cognitive Deficits in Pentylenetetrazole‐Induced Mice Model

ChemistryOpen, EarlyView.
Microwave synthesis yielded 2‐(5‐cyclopropyl‐6‐thioxo‐1,3,5‐thiadiazinan‐3‐yl)acetic acid, confirmed by infrared, nuclear magnetic resonance, and electron ionization mass spectrometry. In a pentylenetetrazole‐induced epilepsy model, it countered oxidative stress by boosting antioxidant enzymes (catalase, peroxidase, superoxide dismutase, glutathione ...
Tahir Iqbal, Murad A. Mubaraki, Ahmad Khushal, Amena Arif, Fozia Fozia, Shahid Ali Shah, Ijaz Ahmad, Rasool Khan, Najeeb Ur Rehman, Ziaullah Ziaullah   +9 more
wiley   +1 more source

Neurosteroids, Microbiota, and Neuroinflammation: Mechanistic Insights and Therapeutic Perspectives. [PDF]

Int J Mol Sci
Tahri A, Niccolai E, Amedei A.
europepmc   +1 more source

Abrupt and Severe Onset of Dystonia, Chorea and Hemiplegic Episodes in a Young Boy with a Novel Heterozygous Missense Variant in the GTPase Domain of RHOBTB2

Movement Disorders Clinical Practice, EarlyView.
Phuong T. Hoang, Ian O. Bledsoe, Marta San Luciano   +2 more
wiley   +1 more source

Evaluation of the Sedative Activity of Naringenin: In Vivo Study with Pharmacokinetics and Molecular Docking Insights

ChemistryOpen, EarlyView.
The study investigates the sedative potential of naringenin (NAR) through in vivo and in silico approaches. NAR significantly enhances sleep duration and reduces latency in mice, especially when combined with diazepam. Molecular docking shows strong binding to GABAA receptors, suggesting a GABAergic mechanism.
Dipu Bishwas, Md. Shimul Bhuia, Salehin Sheikh, Mohammed Alfaifi, Abdul Malik, Nikhat J. Siddiqui, Divya Jain, Mehedi Hasan Bappi, Muhammad Torequl Islam   +8 more
wiley   +1 more source

Comparative analysis of isoxazoline activity on human and canine GABA receptors expressed in Xenopus oocytes. [PDF]

Parasit Vectors
Sager H, Sarr A, Kuntz E, Rufener L.
europepmc   +1 more source

Fecal Metaproteomics as a Tool to Monitor Functional Modifications Induced in the Gut Microbiota by Ketogenic Diet: A Case Study

PROTEOMICS, EarlyView.
ABSTRACT Metaproteomics is a valuable approach to characterize the biological functions involved in the gut microbiota (GM) response to dietary interventions. Ketogenic diets (KDs) are very effective in controlling seizure severity and frequency in drug‐resistant epilepsy (DRE) and in the weight loss management in obese/overweight individuals.
Alessandro Tanca, Simona Masia, Piero Giustacchini, Sergio Uzzau   +3 more
wiley   +1 more source

The Involvement of the Endocannabinoid, Glutamatergic, and GABAergic Systems in PTSD. [PDF]

Int J Mol Sci
Grzesińska AD.
europepmc   +1 more source

GABAergic mechanisms of excitation and hypersynchrony in adult rat hippocampus [PDF]

, 2003
Uusisaari, Marylka
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