Results 241 to 250 of about 449,429 (310)

Comparative Efficacy of Elinzanetant Versus Other Non‐Hormonal Pharmaceutical Therapies for the Treatment of Moderate‐to‐Severe Vasomotor Symptoms Associated With Menopause: A Network Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Elinzanetant, a novel, dual neurokinin‐targeted therapy, has been approved in various geographies for the treatment of moderate‐to‐severe vasomotor symptoms (VMS) associated with menopause. Objective To compare the efficacy of elinzanetant with non‐hormonal pharmaceutical treatments (nHT) in alleviating VMS.
Piotr Wojciechowski, Klaudia Kolonko, Andromachi Giannopoulou, Beata Smela, Elżbieta Olewinska, Kristina Rosa Bolling, Jenifer Sassarini, Lee P. Shulman, Vikram Talaulikar   +8 more
wiley   +1 more source

Effect of Salinity Stress on Gut–Brain–Gonad Axis in the Red‐Eared Slider (Trachemys scripta elegans)

Integrative Zoology, EarlyView.
The increase in salinity leads to changes in the gut microbiota and metabolites of Trachemys scripta elegans, affecting the synthesis and secretion of neurotransmitters or precursors, which can inhibit the secretion of reproductive hormones and affect the self‐renewal and differentiation process of spermatogonial stem cells.
Qiongyu Zhang, Na Li, Xue Tang, Hanru Chen, Meiling Hong, Li Ding   +5 more
wiley   +1 more source

Sex‐Specific Involvement of Gut Microbiota in Behavioral and Endocrine Responses to Chronic Predator Odor in Brandt's Voles

Integrative Zoology, EarlyView.
18 days of predator odor exposure altered gut microbiota, increased anxiety‐like behaviors, and elevated hypothalamic–pituitary–adrenal axis activity in Brandt's voles, with males showing behavioral habituation and females remaining sensitive. Cecal microbiota transplantation experiments confirmed that only female recipients of microbiota from predator‐
Chen Gu, Ruiping Xu, Baofa Yin, Ruiyong Wu, Youheng Wei, Dehua Wang, Wanhong Wei   +6 more
wiley   +1 more source

The Effect of Benzodiazepines on Catatonia: A Systematic Review and Meta‐Analysis

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Catatonia is a complex psychomotor syndrome associated with various psychiatric and somatic underlying disorders. Current treatment protocols include benzodiazepines and electroconvulsive therapy (ECT). Despite their widespread use, systematic evidence regarding efficacy and optimal benzodiazepine dosage remains limited.
L. Bot, B. Schotsman, E. Oostra, A. W. Hoogendoorn, B. W. C. Storosum, C. H. M. Planting, H. M. Heller, J. J. B. van der Vlugt, J. G. van Mill, L. J. C. A. Smarius, M. S. Oudijn, M. S. van Noorden, S. M. M. Lange, Y. D. van der Werf, E. van Exel   +14 more
wiley   +1 more source

Neurotransmitter-Mediated Signaling in Glioblastoma and Glial Tumors: Biology and Therapeutic Opportunities. [PDF]

Oncol Res
Tralongo P, Ballato M, Zuccalà V, Fiorentino V, Giordano W, Casili G, Bellinghieri F, Caruso G, Angileri FF, Fadda G, Martini M, Caffo M.   +11 more
europepmc   +1 more source

Artificial intelligence in the assessment of epilepsy-related genetic mutations: Learned from GABA_A receptors and GABA transporter 1. [PDF]

Epilepsia Open
Wang J, Kang JQ.
europepmc   +1 more source

GABA-Producing Bacteria as Potential Psychobiotics in Gut-Brain Axis Regulation. [PDF]

Int J Mol Sci
Zielińska E, Kycia K, Mikołajczuk-Szczyrba A, Piłka N, Juszczuk-Kubiak E.   +4 more
europepmc   +1 more source

A malignant symbiosis: The neuro-metabolic symphony rewires the tumor microenvironment. [PDF]

Neoplasia
Zhang Z, Jia Y, Liu T, Wang S, Liu L.
europepmc   +1 more source

GABA-mediated regulation of lipid metabolism: a conserved relation with diverse physiological significances. [PDF]

Front Physiol
Pradhan S, Nava S, Hill K, Ochoa-Repáraz J, Sharma K.   +4 more
europepmc   +1 more source