Results 261 to 270 of about 114,819,381 (306)
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Benzodiazepine interactions with GABA receptors
Neuroscience Letters, 1984Benzodiazepines (BZs) produce most, if not all, of their pharmacological actions by specifically enhancing the effects of endogenous and exogenous GABA that are mediated by GABAA receptors. This potentiation consists in an increase of the apparent affinity of GABA for increasing chloride conductance without increase in its efficacy and, on the single ...
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GABA-B Receptors in Drosophila
2010Drosophila melanogaster, the "fruit fly," is being increasingly used as an experimental model in neurosciences, including neuropharmacology. The advantages of Drosophila over typical mammalian models in neuropharmacology include better access to genetic manipulation and the availability of almost unlimited numbers of experimental subjects at relatively
Hari, Manev, Svetlana, Dzitoyeva
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GABA Receptor molecules of insects
1993Receptors for 4-aminobutyric acid (GABA) have been identified in both central and peripheral nervous systems of several invertebrate phyla. To date, much of the information derived from physiological and biochemical studies on insect GABA receptors relates to GABA-gated chloride channels that show some similarities with vertebrate GABAA receptors. Like
Anthony, N. M. +2 more
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Annals of the New York Academy of Sciences, 1990
P C, Waldmeier, P A, Baumann
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P C, Waldmeier, P A, Baumann
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GABA Receptors and the Pharmacology of Sleep
2017Current GABAergic sleep-promoting medications were developed pragmatically, without making use of the immense diversity of GABAA receptors. Pharmacogenetic experiments are leading to an understanding of the circuit mechanisms in the hypothalamus by which zolpidem and similar compounds induce sleep at α2βγ2-type GABAA receptors.
Wisden, W, Yu, X, Franks, NP
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Presynaptic Ionotropic GABA Receptors
2007Following the classical work on presynaptic inhibition in the spinal cord, recent work has revealed an astonishing abundance and diversity of presynaptic ionotropic GABA receptors. While modern techniques allow for detailed studies at the cellular and molecular level in almost all regions of the CNS, our understanding of the function of such receptors ...
Andreas, Draguhn +2 more
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Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1997
K, Kuriyama, M, Hirouchi
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K, Kuriyama, M, Hirouchi
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