Salivary biomarkers in sleep‐related disorders
Abstract The exploration of salivary biomarkers has emerged as a promising avenue in the diagnosis and management of sleep‐related disorders, such as obstructive sleep apnea (OSA), insomnia, and sleep deprivation. Saliva is a noninvasive biofluid that contains a wealth of biological markers, reflecting both local and systemic physiological changes ...
Chuan Xiang Li +9 more
wiley +1 more source
GABA<sub>A</sub> receptor agonists modulate intracellular Ca<sup>2+</sup> levels in activated human CD4<sup>+</sup> T cells. [PDF]
Korol SV +4 more
europepmc +1 more source
Bias in, symbolic compliance out? GPT's reliance on gender and race in strategic evaluations
Abstract Research summary Organizations are increasingly using large language models (LLMs) to support strategic evaluations. We examine whether and how these systems rely on gender and race. We asked GPT to evaluate identical startup pitches varying only the founder's name, shaping gender and race perceptions.
Tristan L. Botelho, Qingyang (Iris) Wang
wiley +1 more source
Structural basis for activation and potentiation in a human α5β3 GABA<sub>A</sub> receptor. [PDF]
Cowgill J +4 more
europepmc +1 more source
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão +12 more
wiley +1 more source
Precision phenotyping of elevated arousal in posttraumatic stress disorder: implications for personalized GABAergic pharmacotherapy. [PDF]
Vasquez VR, Howlett JR.
europepmc +1 more source
Field immobilisation of adult Weddell seals using intramuscular butorphanol and midazolam
Abstract Background When working with free‐ranging phocid seals, methods of chemical immobilisation require ongoing refinement to reduce complications, particularly apnoea, during research procedures. Methods Adult Weddell seals (n = 20) at Cape Crozier, Antarctica, were chemically immobilised with intramuscular injection of butorphanol and midazolam ...
Rachel R. Holser +5 more
wiley +1 more source
Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease
This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin +5 more
wiley +1 more source
Pharmacological principles for safe benzodiazepine and Z-drug dose reduction. [PDF]
Horowitz M +8 more
europepmc +1 more source

