Results 91 to 100 of about 163,092 (297)

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Reduced GABA Levels in the ACC of Actively Drinking High Risk Individuals Compared to Recently Detoxified Alcohol-Dependent Patients

Journal of Integrative Neuroscience
Background: Acute gamma-aminobutyric acid (GABAergic) effects of alcohol consumption are well-known, whereas prior research has yielded inconsistent findings regarding on adaptations of the GABAergic neurotransmitter system to chronic ...
Gianna Spitta, Tobias Gleich, Lea Mascarell Maricic, Annika Rosenthal, Florian Schubert, Semiha Aydin, Andreas Heinz, Jürgen Gallinat   +7 more
doaj   +1 more source

Chronic unpredictable mild stress induced depression-like behaviours and glutamate-glutamine cycling dysfunctions in both blood and brain of mice

Pharmaceutical Biology, 2019
Context: Currently, there is no cure or early preclinical diagnostic assay available for depression. Recently, depression has been observed in association with metabolic abnormalities of the glutamate (Glu)–glutamine (Gln) cycling, which is regulated by ...
Ya-Ping Chen, Chuang Wang, Jiang-Ping Xu
doaj   +1 more source

Pre- And Postsynaptic Effects of Taurine and Gaba in the Cockroach Central Nervous System [PDF]

, 1979
B. Hue, M. Pelhate, J Chanelet
openalex   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Mechanisms by which human blood platelets accumulate glycine, gaba and amino acid precursors of putative neurotransmitters [PDF]

, 1972
David J. Boullin, A. R. Green
openalex   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

Clinical Utility of Zuranolone for Postpartum Depression: A Narrative Review

Neuropsychiatric Disease and Treatment
Athanasia Giannopoulos,1 Joshna Singh,2 Kristina M Deligiannidis1,3 1Division of Psychiatry Research, Zucker Hillside Hospital, Northwell Health, New York, NY, USA; 2Department of Psychiatry, Jacobs School of Medicine and Biomedical Sciences, University ...
Giannopoulos A, Singh J, Deligiannidis KM   +2 more
doaj  

BIOLOGICAL ACTIONS In vivo AND In vitro OF TWO γ‐AMINOBUTYRIC ACID (GABA) ANALOGUES: β‐CHLORO GABA AND β‐PHENYL GABA [PDF]

, 1974
Nguyen T. Buu, N. M. van Gelder
openalex   +1 more source

Efficacy and tolerability of perampanel as add‐on therapy in Dravet syndrome: A prospective real‐world study

Epilepsia Open, EarlyView.
Abstract Objective To investigate the efficacy and tolerability of perampanel (PER) on Dravet syndrome in China by a prospective real‐world study. Methods We prospectively enrolled children with Dravet syndrome from the neurology clinic of Shenzhen Children's Hospital from September 2020 to October 2021.
Han Wang, Hong Chen, Xin Ding, Xueyan Cao, Jiahui Mai, Huafang Zou, Dongfang Zou, Yanwei Zhu, Jianxiang Liao, Dezhi Cao   +9 more
wiley   +1 more source