Results 101 to 110 of about 163,092 (297)

Resting‐state functional connectivity changes with microburst vagus nerve stimulation therapy

Epilepsia Open, EarlyView.
Abstract Objective Microburst vagus nerve stimulation (μVNS) may reduce seizure frequency in drug‐resistant epilepsy (DRE) via targeted thalamic plasticity. We prospectively investigated the role of thalamic resting‐state functional connectivity (rsFC) in μVNS effects and hypothesized a relationship between thalamic rsFC and long‐term seizure frequency
Jane B. Allendorfer, Rodolphe Nenert, Elhum Shamshiri, Giovanni Ranuzzi, Jason Begnaud, Ryan Verner, Jerzy P. Szaflarski, for the Microburst Study Group, Rebecca O’Dwyer, Michael Macken, Blake Newman, Cornelia Drees, Danielle McDermott, Lesley Kaye, Mesha Gay Brown, Muhammad Zafar, William Tatum, Selim Benbadis, Pegah Afra, Zeenat Jaisani, Kristl Vonck   +20 more
wiley   +1 more source

A New Synthesis and the Crystal Structure of (RS)-2-Hydroxy-4-aminobutyric Acid Hydrochloride Monohydrate, an Inhibitor of GABA Uptake. [PDF]

, 1979
Lotte Brehm, Povl Krogsgaard‐Larsen, Tapani A. Pakkanen, T.A. Pakkanen, Rolf Servin, Hans Sternerup, Lars‐Göran Wistrand, L. Nørskov, Gustav Schroll   +8 more
openalex   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Influence of Harvesting Time on Phytochemical Content of Colored Brown and Parboiled Rice

AGRIVITA Journal of Agricultural Science
Colored rice receives more attention from consumers because of its high phytochemicals and antioxidant activity beneficial to health. The aims of this investigation were to quantify the important phytochemicals and antioxidant activity in three varieties
Nattareeporn Rodnuch, Kiattisak Burum, Chorkaew Aninbon   +2 more
doaj   +1 more source

Aging and GABA

Aging, 2018
Stephan P. Swinnen, Stephan P. Swinnen, Celine Maes, Koen Cuypers   +3 more
openaire   +3 more sources

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Effect of acetaminophen use on GABA, NMDA, and synaptic plasticity-related genes in the immature mouse brain: A preliminary study

The EuroBiotech Journal
Background/aim: Acetaminophen is frequently used as an analgesic during pregnancy. The purpose of the present study was to evaluate the effects of acetaminophen administered to pregnant mice on the fetal brain, attention, memory, and learning functions ...
Göl Mehmet Fatih, Erdoğan Füsun Ferda, Baydemir Recep, Gök Duygu Kurt, Taheri Serpil, Önal Müge Gülcihan, Şükranlı Zeynep Yılmaz, Güvenilir Ecma, Yora Samed   +8 more
doaj   +1 more source

SCN1A gain of function effects in Dravet syndrome: Insights into clinical phenotypes and therapeutic implications

Epilepsia Open, EarlyView.
Abstract A large number of cases with Dravet syndrome (DS) has been attributed to SCN1A loss of function (LOF), whereas SCN1A gain‐of‐function (GOF) causes early infantile developmental and epileptic encephalopathy (EIDEE) and familial hemiplegic migraine 3.
Yoko Kobayashi Takahashi, Kenshiro Tabata, Shimpei Baba, Eri Takeshita, Noriko Sumitomo, Yuko Shimizu‐Motohashi, Takashi Saito, Eiji Nakagawa, Atsushi Ishii, Shinichi Hirose, Mitsuhiro Kato, Naomichi Matsumoto, Hirofumi Komaki, Ken Inoue   +13 more
wiley   +1 more source

EFFECTS OF γ-AMINOBUTYRIC ACID (GABA), γ-AMINOBUTYRYL CHOLINE (GABA-CH) AND THEIR RELATED SUBSTANCES ON THE CORTICAL ACTIVITY

, 1959
Hidehiko Takahashi, Akira Nagashima, Chikao KOSHINO, Hisashi Takahashi   +3 more
openalex   +2 more sources

1‐Hydroxy‐3‐amino‐pyrrolidone‐2 (HA‐966): a new GABA‐like compound, with potential use in extrapyramidal diseases [PDF]

, 1971
I.L. Bonta, C. J. De Vos, H. Grijsen, F. C. Hillen, E. L. Noach, Alex Sim   +5 more
openalex   +1 more source