Results 61 to 70 of about 333,224 (356)
Role of nitric oxide synthase on brain GABA transaminase activity and GABA levels
Acta Pharmaceutica, 2018 In an attempt to clarify the controversial role of nitric oxide (NO) in seizures, the effects of NO on brain GABA transaminase (GABA-T) activity and GABA levels were investigated.
Vega Rasgado Lourdes A. +2 more
doaj +1 more source
Antagonism of GABA-B but not GABA-A receptors in the VTA prevents stress- and intra-VTA CRF-induced reinstatement of extinguished cocaine seeking in rats [PDF]
, 2016 Stress-induced reinstatement of cocaine seeking requires corticotropin releasing factor (CRF) actions in the ventral tegmental area (VTA). However the mechanisms through which CRF regulates VTA function to promote cocaine use are not fully understood ...
Baker, David A. +5 more
core +2 more sources
Arthritis Care &Research, Accepted Article.As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Co‐morbid depression is prevalent in adults with IA, affecting 15 to 39% of people. Whilst pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox +3 more
wiley +1 more source
Neuroprotective properties of GABA and its derivatives in diabetic encephalopathy in old animals
Фармация и фармакология (Пятигорск), 2023 The aim of the work was to evaluate the GABA neuroprotective properties and its structural analogues in old animals after seven months of hyperglycemia.Materials and methods. Diabetes mellitus was modeled in white outbred male rats (12 months old) by the
I. N. Tyurenkov +9 more
doaj +1 more source
GABA-B controls persistent Na+ current and coupled Na+-activated K+ current [PDF]
, 2017 The GABA-B receptor is densely expressed throughout the brain and has been implicated in many CNS functions and disorders, including addiction, epilepsy, spasticity, schizophrenia, anxiety, cognitive deficits, and depression, as well as various aspects ...
Butler, Alice +5 more
core +2 more sources
Advanced Science, EarlyView.Mitochondria across the entire neuromuscular system have been comprehensively reconstructed at different developmental stages using 3D electron microscopy. Fundamental structural principles related to synaptic function are preserved across development, and these morphologies are adapted to ensure effective neural circuit function.
J. Alexander Bae +9 more
wiley +1 more source
Journal of Plant Interactions, 2020 In this study, the impacts of exogenous melatonin on freezing stress mitigation in pistachio (Pistacia vera L.) seedlings (30-days old) were investigated.
Adeleh Barand +3 more
doaj +1 more source
A Molecularly Defined Medullary Network for Control of Respiratory Homeostasis
Advanced Science, EarlyView.The dynamic interplay between central respiratory chemoreceptors and the respiratory central pattern generator is essential for maintaining stable respiratory rhythm and patterns, particularly during sleep. This study offers novel insights into the anatomical, molecular, and functional characteristics of a medullary network involving the nucleus ...
Tianjiao Deng +16 more
wiley +1 more source
European Journal of Biology, 2022 Objective: Global warming causes many different stresses for plants. High-temperature stress is one of the important problems caused by global warming. Plants develop various tolerance mechanisms to protect themselves against these stresses.
Nihal Gören Sağlam +2 more
doaj +1 more source
Advanced Science, EarlyView.This study examines the effects of Shank3 mutation on the mesoaccumbens pathway using a Shank3‐deficient rat model. The findings reveal altered social reward processing in these rats, accompanied by changes in dopaminergic and GABAergic neural activity within the ventral tegmental area (VTA) and dopamine release in the nucleus accumbense (NAc ...
Marie Barbier +4 more
wiley +1 more source