Results 281 to 290 of about 171,989 (360)
Summary Background and Objectives Knowledge on patient care gaps of prurigo nodularis (PN) is limited. This retrospective chart review (ADVANCE PN) investigated unmet medical needs and gaps in diagnostics, treatment, and management of patients with PN in routine care in Germany.
Ralph von Kiedrowski+5 more
wiley +1 more source
Acetylcholine in the hippocampus: problems and achievements. [PDF]
Dobryakova YV+3 more
europepmc +1 more source
Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes+6 more
wiley +1 more source
From bugs to brain: unravelling the GABA signalling networks in the brain-gut-microbiome axis. [PDF]
Belelli D+5 more
europepmc +1 more source
Type 1 Diabetes: A Guide to Autoimmune Mechanisms for Clinicians
Abstract Type 1 diabetes (T1D) results from the destruction of pancreatic beta cells by autoreactive T lymphocytes, leading to insulin deficiency and lifelong insulin dependence. It develops in genetically predisposed individuals, triggered by environmental or immunological factors.
François‐Xavier Mauvais+1 more
wiley +1 more source
Preferential superficial cortical layer activation during seizure propagation
Abstract Objective Focal cortical seizures travel long distances from the onset zone, but the long‐distance propagation pathways are uncertain. In vitro and in vivo imaging techniques have investigated the local spread of seizures but did not elucidate long‐distance spread. Furthermore, classical studies in slices suggested seizure spread locally along
Anastasia Brodovskaya+4 more
wiley +1 more source
Sleep Aid Effect and Mechanism of Semen Zizyphi Spinosae Extract Enriched With Jujuboside and Jujubogenin in Sleep-Deprived Zebrafish. [PDF]
Wang W+8 more
europepmc +1 more source
Abstract Objective This study was undertaken to describe a case series of Brazilian new onset refractory status epilepticus (NORSE) patients and evaluate the sensitivity and specificity of a clinical score to predict cryptogenic etiology (c‐NORSE score) after autoimmune encephalitis (AE) testing.
João Henrique Fregadolli Ferreira+42 more
wiley +1 more source
The Effect of Antibiotics on the Nervous System: Importance for Anesthesiology and Intensive Care. [PDF]
Radkowski P+5 more
europepmc +1 more source
Abstract Objective This real‐world, retrospective, multicenter study aims to investigate the effectiveness of highly purified cannabidiol (CBD) in a large cohort of patients with epilepsy of genetic etiology due to an identified monogenic cause. Additionally, we examine the potential relationship between specific genetic subgroups and treatment ...
Emanuele Cerulli Irelli+68 more
wiley +1 more source