Results 101 to 110 of about 2,290,618 (347)
Protein connectivity in chemotaxis receptor complexes [PDF]
, 2015 The chemotaxis sensory system allows bacteria such as Escherichia coli to swim towards nutrients and away from repellents. The underlying pathway is remarkably sensitive in detecting chemical gradients over a wide range of ambient concentrations. Interactions among receptors, which are predominantly clustered at the cell poles, are crucial to this ...
arxiv +1 more source
Output of neurogliaform cells to various neuron types in the human and rat cerebral cortex
Frontiers in Neural Circuits, 2007 Neurogliaform cells in the rat elicit combined GABAA and GABAB receptor-mediated postsynaptic responses on cortical pyramidal cells and establish electrical synapses with various interneuron types.
Szabolcs Oláh +6 more
doaj +1 more source
Journal of Neuroscience, 2013 Ambient GABA in the brain tonically activates extrasynaptic GABAA receptors, and activity-dependent changes in ambient GABA concentration can also activate GABAB receptors.
Wucheng Tao +3 more
semanticscholar +1 more source
Adhesion of membranes via receptor-ligand complexes: Domain formation, binding cooperativity, and active processes [PDF]
, 2009 Cell membranes interact via anchored receptor and ligand molecules. Central questions on cell adhesion concern the binding affinity of these membrane-anchored molecules, the mechanisms leading to the receptor-ligand domains observed during adhesion, and the role of cytoskeletal and other active processes.
arxiv +1 more source
Glia, EarlyView.Comprehensive analysis of cortical astrocyte gene expression across the lifespan. Profiling dynamic changes of key astrocyte genes reveals functional shifts. Astrocytes contribute to gene‐length‐dependent transcription decline in the aging brain. ABSTRACT Astrocytes are the most abundant glial cell type in the central nervous system (CNS).
Xiaoran Wei +2 more
wiley +1 more source
Neurobiology of Stress, 2016 The GABAergic synapse undergoes structural and functional maturation during early brain development. Maternal stress alters GABAergic synapses in the pup's brain that are associated with the pathophysiology of neuropsychiatric disorders in adults ...
Bovorn Veerawatananan +2 more
doaj +1 more source
Astroglial CB1 Reveal Sex‐Specific Synaptic Effects of Amphetamine
Glia, EarlyView.Astroglial CB1R mediates long‐term synaptic plasticity (LTD) in the Nucleus accumbens. Amphetamine saturates adenosine receptors and blocks LTD in males, but not females. Locomotor effects of amphetamine require astroglial CB1R in males, but not in females.
Yamuna Mariani +15 more
wiley +1 more source
Neurobiology of Disease, 2014 We compared the effects of three missense mutations in the GABAA receptor γ2 subunit on GABAA receptor assembly, trafficking and function in HEK293T cells cotransfected with α1, β2, and wildtype or mutant γ2 subunits.
Xuan Huang +3 more
doaj
Advances in Pharmacological Sciences, 2012 Despite decades of basic and clinical research, our understanding of how benzodiazepines tend to lose their efficacy over time (tolerance) is at least incomplete.
C. Vinkers, B. Olivier
semanticscholar +1 more source
Research progress on the mechanisms of pain empathy
Ibrain, EarlyView.This article is related to the graphical research progress of pain empathy, starting with the description of the pain matrix and mirror neurons. Based on the pain matrix and mirror neurons, pain empathy results from the combined action of brain regions such as the anterior cingulate cortex, insula, prefrontal cortex, and amygdala and regulatory ...
Shuangshuang Liu +5 more
wiley +1 more source