Results 81 to 90 of about 1,283,132 (206)

Increased motor-impairing effects of the neuroactive steroid pregnanolone in mice with targeted inactivation of the GABAA receptor gamma2 subunit in the cerebellum

Frontiers in Pharmacology, 2016
Endogenous neurosteroids and neuroactive steroids have potent and widespread actions on the brain via inhibitory GABAA receptors. In recombinant receptors and genetic mouse models their actions depend on the alpha, beta and delta subunits of the receptor,
Elli Leppä, Anni-Maija Tuulikki Linden, M. Isabel Aller, Peer Wulff, Olga Vekovischeva, Bernhard Lüscher, Hartmut Lüddens, William Wisden, Esa R Korpi   +8 more
doaj   +1 more source

Caracterização do efeito ansiolítico de drogas em ratos pré-expostos no labirinto em cruz elevado [PDF]

, 2004
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Farmacologia.Um aumento seletivo e significativo na exploração dos braços abertos do labirinto em cruz elevado (LCE) é observado após a ...
Bertoglio, Leandro José
core  

The Effects of Variation in the GABAA Receptor Gene on Anxious Depression are Mediated by the Functional Connectivity Between the Amygdala and Middle Frontal Gyrus

Neuropsychiatric Disease and Treatment
Juan Qiao,1,2 Shiwan Tao,2 Yurong Sun,3,4 Jiabo Shi,2,5 Yu Chen,2,5 Shui Tian,3,4 Zhijian Yao,2,5 Qing Lu3,4 1Department of Psychology, Xuzhou East Hospital Affiliated to Xuzhou Medical University, Xuzhou, People’s Republic of China; 2Department of ...
Qiao J, Tao S, Sun Y, Shi J, Chen Y, Tian S, Yao Z, Lu Q   +7 more
doaj  

Alterations in gamma-aminobutyric acid and glutamate neurotransmission linked to intermittent theta-burst stimulation in depression: a sham-controlled study

Translational Psychiatry
Gamma-aminobutyric acid (GABA) and glutamate are implicated in the antidepressant effects of repetitive transcranial magnetic stimulation (rTMS), though findings from magnetic resonance spectroscopy (MRS) are inconsistent.
Linda Steinholtz, Robert Bodén, Anders Wall, Mark Lubberink, David Fällmar, Jonas Persson   +5 more
doaj   +1 more source

Localization of GABAA receptor α-subunit mRNAs in relation to receptor subtypes

, 1989
The distribution of 3 {GABAA} receptor α-subunit mRNAs in various regions of bovine brain has been investigated using in situ hybridization. Whereas the α2- and α3-transcripts are of low abundance in all regions except striatum, the α1-transcript is ...
Barnard, Eric A., Hunt, Stephen P., Darlison, Mark G., Wisden, William, Morris, Brian J.   +4 more
core   +1 more source

Effect of Heat Stress on the Expression of GABA Receptor mRNA in the HPG Axis of Wenchang Chickens

Brazilian Journal of Poultry Science
We investigated the effect of heat stress (HS) on the expression of the GABA receptor in the hypothalamic-pituitary-gonadal (HPG) axis of Wenchang chickens.
LJ Xie, XZ Xie, YW Zhou, C Liang, YY Jiang, Z Chen   +5 more
doaj   +1 more source

GABAA Receptor [PDF]

Science-Business eXchange, 2010
Husseini K. Manji, Jorge Quiroz, R. Andrew Chambers, Anthony Absalom, David Menon, Patrizia Porcu, A. Leslie Morrow, Wolfgang Fleischhacker, Naheed (Max) Mirza, Christine A. Franco, Marc N. Potenza, Robert Kessler, Ronald L. Cowan, Daniel Hoyer, Eric J. Nestler, Elizabath C. Warburton, Anthony Absalom, David Menon, David S. Baldwin, Sophie Tambour, John C. Crabbe, Nicole Edgar, Etienne Sibille, Linda Lundstroem, Silvia Gatti McArthur, Will Spooren, R. H. de Rijk, E. R. De Kloet, Michael J. Owens, Chase H. Bourke, Joachim D. Uys, Peter W. Kalivas, Linda Lundstroem, Silvia Gatti McArthur, Will Spooren, Anne M. Andrews, Greg A. Gerhardt, Lynette Daws, Barbara J. Mason, Charles J. Heyser, Seiya Miyamoto, Peter Riederer, Siegfried Hoyer, Suzanne H. Mitchell, Harriet de Wit, Matthew I. Palmatier, Rick A. Bevins, Jill B. Becker, C. Neill Epperson, Gorkem Yararbas, Sakire Pogun, Michael M. Morgan, MacDonald J. Christie, Michael M. Morgan, MacDonald J. Christie, Ben J. Harrison, Christos Pantelis, Seiya Miyamoto, Andrew Young   +58 more
openaire   +2 more sources

The GABAA receptors [PDF]

Biochemical Journal, 1995
openaire   +2 more sources

Therapeutic potential of rutin in premenstrual depression: evidence from in vivo and in vitro studies

Frontiers in Pharmacology
IntroductionPremenstrual dysphoric disorder (PMDD) is a cyclical mood disorder that severely affects the daily life of women of reproductive age. Most of the medications being used clinically have limitations such as low efficacy, side effects, and high ...
Xiangjun Wang, Xiaowen Xia, Xianliang Song, Yi Zhou, Mingyu Ma, Yashuang Ren, Xitai Chen, Zenghui Xia, Yinghui Guo, Chunhong Song   +9 more
doaj   +1 more source

Impact of subunit positioning on GABAA receptor function

, 2006
The major isoforms of the GABAA (gamma-aminobutyric acid type A) receptor are composed of two alpha, two beta and one gamma subunit. Thus alpha and beta subunits occur twice in the receptor pentamer.
Minier, F, Baur, R, Sigel, E, Boulineau, N   +3 more
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