Results 131 to 140 of about 80,549 (314)

Therapeutic potential of rutin in premenstrual depression: evidence from in vivo and in vitro studies

Frontiers in Pharmacology
IntroductionPremenstrual dysphoric disorder (PMDD) is a cyclical mood disorder that severely affects the daily life of women of reproductive age. Most of the medications being used clinically have limitations such as low efficacy, side effects, and high ...
Xiangjun Wang, Xiaowen Xia, Xianliang Song, Yi Zhou, Mingyu Ma, Yashuang Ren, Xitai Chen, Zenghui Xia, Yinghui Guo, Chunhong Song   +9 more
doaj   +1 more source

The alpha1 subunit of the GABA(A) receptor modulates fear learning and plasticity in the lateral amygdala. [PDF]

, 2009
Synaptic plasticity in the amygdala is essential for emotional learning. Fear conditioning, for example, depends on changes in excitatory transmission that occur following NMDA receptor activation and AMPA receptor modification in this region.
Cook, James M, Fanselow, Michael S, Godsil, Bill P, Homanics, Gregg E, Houser, Carolyn R, June, Harry L, Linn, Michael L Van, O'Dell, Tom J, Peng, Zechun, Saab, Faysal, Wiltgen, Brian J   +10 more
core  

Structural and functional characterization of the gamma 1 subunit of GABAA/benzodiazepine receptors. [PDF]

, 1990
S. Ymer, Andreas Draguhn, William Wisden, P. Werner, Kari Keinänen, Peter R. Schofield, Rolf Sprengel, Dolan B. Pritchett, P. H. Seeburg   +8 more
openalex   +1 more source

Use of transcutaneous spinal cord stimulation to explore inhibitory and facilitatory circuits in muscles of the human lower limb

Experimental Physiology, EarlyView.
Abstract The aim of this study was to explore the primary afferent depolarization mechanism, to determine whether the soleus transspinal evoked potential (TEP), elicited through transcutaneous spinal cord stimulation over the L1–L2 level, is modulated by presynaptic inhibition and heteronymous facilitation, similar to the Hoffmann (H) reflex, elicited ...
Julia Sordet, Maria Papaiordanidou, Nicolas Amiez, Ioannis Amiridis, Jean‐Pierre Quenot, Alain Martin   +5 more
wiley   +1 more source

Age-related decrease of GABAA receptor subunits and glutamic acid decarboxylase in the rat inferior colliculus [PDF]

, 1994
Antonia Gutiérrez, Zafar U. Khan, SJ Morris, AL de Blas   +3 more
openalex   +1 more source

Changes in the cortical GABAergic inhibitory system with ageing and ageing‐related neurodegenerative diseases

The Journal of Physiology, EarlyView.
Abstract figure legend With ageing and age‐related neurodegenerative diseases, the amount of GABA and GABAergic inhibition as well as the modulation (indicated by sine wave) of GABAergic inhibition is reduced, whereas excitation is increased. In many parts of the brain, this leads to a mismatch of facilitatory (green neurons) and inhibitory (red ...
Wolfgang Taube, Benedikt Lauber
wiley   +1 more source

Immunocytochemical detection of astrocyte GABAA receptors in cat visual cortex. [PDF]

, 1993
A. M. Rosier, Lut Arckens, Guy A. Orban, Frans Vandesande   +3 more
openalex   +1 more source

Synaptic communication within the microcircuits of pyramidal neurons and basket cells in the mouse prefrontal cortex

The Journal of Physiology, EarlyView.
Abstract figure legend Basket cells represent critical building blocks of neuronal circuits in cortical regions by providing GABAergic innervation to the perisomatic region of their postsynaptic partners. In the mouse prelimbic cortex, the two basket cell types expressing parvalbumin or cholecystokinin/type I cannabinoid receptor receive unitary ...
Zsuzsanna Fekete, Filippo Weisz, Mária Rita Karlócai, Judit M. Veres, Tibor Andrási, Norbert Hájos   +5 more
wiley   +1 more source

Pathologically Activated Neuroprotection via Uncompetitive Blockade of \u3cem\u3eN\u3c/em\u3e-Methyl-d-aspartate Receptors with Fast Off-rate by Novel Multifunctional Dimer Bis(propyl)-cognitin [PDF]

, 2010
Uncompetitive N-methyl-d-aspartate (NMDA) receptor antagonists with fast off-rate (UFO) may represent promising drug candidates for various neurodegenerative disorders.
Fu, Hongjun, Han, Yifan, Huang, Pingbo, Li, Chaoying, Li, Fushun, Li, Wenming, Luo, Jialie, Ma, Dik-Lung, Pang, Yuanping, Peoples, Robert W., Tang, Jing, Wang, Qinwen, Xia, Jun, Zhao, Yuming   +13 more
core   +1 more source

Membrane trafficking of synaptic adhesion molecules

The Journal of Physiology, EarlyView.
Abstract figure legend Synaptic cellular adhesion molecules are surface transmembrane receptors that have been shown to internalize via endocytosis, and possibly also recycle, in a process that has been linked to the function and the turnover of the synaptic contact site.
Cristian A. Bogaciu, Silvio O. Rizzoli
wiley   +1 more source