Results 91 to 100 of about 39,325 (214)
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, Volume 20, Issue 6, Page 1420-1428, June 2026.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Annals of Neurology, Volume 99, Issue 6, Page 1468-1479, June 2026.Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo +16 more
wiley +1 more source
Brain and Behavior, Volume 16, Issue 6, June 2026.In treating Qi stagnation type insomnia, the combination of traditional Chinese medicine and acupuncture can improve sleep quality, alleviate anxiety and depression, and improve physical fitness. Compared to using traditional Chinese medicine decoction alone for treatment, the combination of traditional Chinese medicine decoction and acupuncture has ...
Xue‐Wen Mao, Peng Bai
wiley +1 more source
Caffeine and Headache: Exploring the Multifaceted Relationship
Brain and Behavior, Volume 16, Issue 6, June 2026.ABSTRACT Purpose To explore the multifaceted relationship between caffeine and headache disorders, focusing on its dual role as both an analgesic and a potential trigger and to summarize the mechanisms underlying its anti‐nociceptive effects. Method This narrative review synthesizes evidence from experimental, clinical, and epidemiological studies on ...
Mona Hussein +6 more
wiley +1 more source
Epileptic Disorders, Volume 28, Issue 3, Page 775-785, June 2026.Abstract Objective Patients with drug‐resistant epilepsy (DRE) typically take multiple anti‐seizure medications (ASMs) and are at risk of treatment‐related adverse events (AEs). This study assessed the impact of cenobamate monotherapy or dual therapy in patients with drug‐resistant epilepsy.
Álvaro Sánchez‐Guijo Benavente +13 more
wiley +1 more source
An iEEG investigation on sex‐specific differences in seizure duration
Epilepsia Open, Volume 11, Issue 3, Page 912-921, June 2026.Abstract Objective Male people with epilepsy (mPWE) are at higher risk for bilateral tonic–clonic seizures (BTCs) and sudden unexpected death in epilepsy (SUDEP) compared to female people with epilepsy (fPWE). Despite major clinical and personal implications, little is known about sex‐specific differences in seizure propagation and termination ...
Paula Albert I Gracenea +4 more
wiley +1 more source
Frontiers in PharmacologyBackgroundAlterations in the GABAergic system contribute to the pathophysiology of neurodevelopmental disorders, including autism spectrum disorder (ASD) and Angelman syndrome (AS), particularly in cases involving large deletions in the 15q11–13 region ...
Giuseppe Cecere +21 more
doaj +1 more source
Epilepsia Open, Volume 11, Issue 3, Page 962-972, June 2026.Abstract Objective Cenobamate (CNB) is a highly effective antiseizure medication (ASM) for focal drug‐resistant epilepsy (DRE); nevertheless, even with CNB treatment and optimized therapy, a substantial proportion of patients continued to experience seizures.
Ilaria Ciullo +8 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 6, June 2026.Gallic acid (GA) dose‐dependently reduced sleep latency and prolonged sleep duration in thiopental sodium‐induced mice, with synergistic effects when combined with diazepam. Molecular docking revealed GA's higher binding affinity (−9.8 kcal/mol) to GABAA receptor (α1 and β2 subunits) than diazepam (−8.4 kcal/mol), suggesting GABAergic potential ...
Noshin Tasnim Yana +13 more
wiley +1 more source