Results 91 to 100 of about 8,190 (170)
, 2017 International audienceIn Huntington's disease (HD), dysfunctional affective processes emerge as key symptoms of disturbances. In human HD and transgenic rat models of the disease, the amygdala was previously shown to have a reduced volume and to carry a ...
Lamirault, Charlotte +11 more
core +1 more source
Insulin-induced Suppression of A-type GABA Receptor Signaling in the INS-1 Pancreatic β-cell Line [PDF]
, 2010 GABA and GABA type A receptor (GABAAR) are expressed in pancreatic β-cells and comprise an autocrine signaling system. How the GABA-GABAAR system is regulated is unknown. In this study, I investigated insulin’s effect on this system in the INS-1 β-cell
Bansal, Pritpal
core
Frontiers in Neural Circuits, 2014 The intercalated paracapsular cells (pcs) are small GABAergic interneurons that form densely populated clusters surrounding the basolateral (BLA) complex of the amygdala.
Anne eMarowsky, Kaspar Emanuel Vogt
doaj +1 more source
Table_2_Diazepam Accelerates GABAAR Synaptic Exchange and Alters Intracellular Trafficking.DOCX
, 2019 Despite 50+ years of clinical use as anxiolytics, anti-convulsants, and sedative/hypnotic agents, the mechanisms underlying benzodiazepine (BZD) tolerance are poorly understood.
Tija C. Jacob (6637730) +4 more
core +1 more source
Communications BiologyThe γ-aminobutyric acid (GABA) type A receptor (GABAAR), a GABA activated pentameric chloride channel, mediates fast inhibitory neurotransmission in the brain. The lipid environment is critical for GABAAR function.
Zixuan Yuan +2 more
doaj +1 more source
Cell- and input-specific expression of the α5-GABAAR in the CA1 area of the mouse hippocampus
, 2018 Dans l'hippocampe, les processus de mémoire et d'apprentissage dépendent fortement de l'inhibition GABAergique, qui est fournis par une population hétérogène d'interneurones (INs) via l'activation de sous-types spécifiques de récepteurs GABA.
Amalyan, Sona
core
Table_1_Diazepam Accelerates GABAAR Synaptic Exchange and Alters Intracellular Trafficking.XLSX
, 2019 Despite 50+ years of clinical use as anxiolytics, anti-convulsants, and sedative/hypnotic agents, the mechanisms underlying benzodiazepine (BZD) tolerance are poorly understood.
Tija C. Jacob (6637730) +4 more
core +1 more source
GABAAR-PPT1 palmitoylation homeostasis controls synaptic transmission and circuitry oscillation
Translational PsychiatryThe infantile neuronal ceroid lipofuscinosis, also called CLN1 disease, is a fatal neurodegenerative disease caused by mutations in the CLN1 gene encoding palmitoyl protein thioesterase 1 (PPT1).
Jia Tong +18 more
doaj +1 more source
The Role of the δ GABA(A) Receptor in Ovarian Cycle-Linked Changes in Hippocampus-Dependent Learning and Memory [PDF]
, 2014 The δ subunit of the GABAAR is highly expressed in the dentate gyrus of the hippocampus where it mediates a tonic extrasynaptic inhibitory current that is sensitive to neurosteroids.
Cushman, Jesse D +3 more
core +1 more source
Maturation of the GABAergic Transmission in Normal and Pathologic Motoneurons
Neural Plasticity, 2011 γ-aminobutyric acid (GABA) acting on Cl−-permeable ionotropic type A (GABAA) receptors (GABAAR) is the major inhibitory neurotransmitter in the adult central nervous system of vertebrates.
Anne-Emilie Allain +6 more
doaj +1 more source