Results 31 to 40 of about 914,049 (192)
Cell Reports, 2021 Summary: Extensive hierarchical yet highly reciprocal interactions among cortical areas are fundamental for information processing. However, connectivity rules governing the specificity of such corticocortical connections, and top-down feedback ...
Shovan Naskar +4 more
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Frontiers in Neural Circuits, 2023 GABAergic inhibitory neurons are the principal source of inhibition in the brain. Traditionally, their role in maintaining the balance of excitation-inhibition has been emphasized.
Melissa Hernández-Frausto +10 more
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Specification and Differentiation of Cerebellar GABAergic Neurons [PDF]
The Cerebellum, 2011 Cerebellar GABAergic projection neurons and interneurons originate from the ventricular neuroepithelium of the cerebellar primordium. However, while projection neurons are born within this germinal layer, interneurons derive from progenitors that delaminate into the prospective white matter.
Ketty, Leto, Ferdinando, Rossi
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Cortical Circuits of Callosal GABAergic Neurons [PDF]
Cerebral Cortex, 2017 Anatomical studies have shown that the majority of callosal axons are glutamatergic. However, a small proportion of callosal axons are also immunoreactive for glutamic acid decarboxylase, an enzyme required for gamma-aminobutyric acid (GABA) synthesis and a specific marker for GABAergic neurons.
Crystal, Rock +4 more
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A Pivotal Genetic Program Controlled by Thyroid Hormone during the Maturation of GABAergic Neurons
iScience, 2020 Summary: Mammalian brain development critically depends on proper thyroid hormone signaling, via the TRα1 nuclear receptor. The downstream mechanisms by which TRα1 impacts brain development are currently unknown. In order to investigate these mechanisms,
Sabine Richard +6 more
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eLife, 2021 The dorsal raphe nucleus (DR) and median raphe nucleus (MR) contain populations of glutamatergic and GABAergic neurons that regulate diverse behavioral functions. However, their whole-brain input-output circuits remain incompletely elucidated.
Zhengchao Xu +14 more
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GABAergic signalling to adult‐generated neurons [PDF]
The Journal of Physiology, 2008 New neurons are continuously generated in discrete regions of the adult brain. In the hippocampus, newly generated cells undergo a step‐wise progression of maturation that is regulated at multiple stages by a variety of physiological and pathological stimuli. Neural progenitors and newborn neurons initially receive exclusively GABAergic synaptic input,
Sean, Markwardt +1 more
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The Reversal Characteristics of GABAergic Neurons: A Neurovascular Model
Journal of Biomechanical Engineering, 2022 Abstract Neurovascular coupling (NVC) is the ability to locally adjust vascular resistance as a function of neuronal activity. Recent experiments have illustrated that NVC is partially independent of metabolic signals. In addition, nitric oxide (NO) has been shown in some instances to provide an important mechanism in altering vascular ...
David, T. +4 more
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PLoS Computational Biology, 2021 The impact of GABAergic transmission on neuronal excitability depends on the Cl--gradient across membranes. However, the Cl--fluxes through GABAA receptors alter the intracellular Cl- concentration ([Cl-]i) and in turn attenuate GABAergic responses, a ...
Aniello Lombardi +3 more
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Frontiers in Synaptic Neuroscience, 2021 Identification of candidate risk genes and alteration in the expression of proteins involved in regulating inhibitory neuron function in various psychiatric disorders, support the notion that GABAergic neuron dysfunction plays an important role in ...
Douglas Asede +4 more
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