Results 41 to 50 of about 914,049 (192)
Acidosis-Induced Dysfunction of Cortical GABAergic Neurons through Astrocyte-Related Excitotoxicity.
PLoS ONE, 2015 BackgroundAcidosis impairs cognitions and behaviors presumably by acidification-induced changes in neuronal metabolism. Cortical GABAergic neurons are vulnerable to pathological factors and their injury leads to brain dysfunction.
Li Huang +5 more
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Genetic Single Neuron Anatomy Reveals Fine Granularity of Cortical Axo-Axonic Cells
Cell Reports, 2019 Summary: Parsing diverse nerve cells into biological types is necessary for understanding neural circuit organization. Morphology is an intuitive criterion for neuronal classification and a proxy of connectivity, but morphological diversity and ...
Xiaojun Wang +18 more
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GABAergic mechanism of propofol toxicity in immature neurons [PDF]
Journal of Neurosurgical Anesthesiology, 2006 Certain anesthetics exhibit neurotoxicity in the brains of immature but not mature animals. Gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the adult brain, is excitatory on immature neurons via its action at the GABAA receptor, due to a reversed transmembrane chloride gradient.
Sibel, Kahraman +3 more
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Origins of Cortical GABAergic Neurons in the Cynomolgus Monkey [PDF]
Cerebral Cortex, 2008 In human most cortical gamma-aminobutyric acidergic (GABAergic) neurons are produced in the proliferative zones of the dorsal telencephalon in contrast to rodents. We report that in cynomolgus monkey fetuses cortical GABAergic neurons are generated in the proliferative zones of the dorsal telencephalon, in addition to the proliferative region of the ...
Petanjek, Zdravko +2 more
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Excitatory GABAergic Effects in Striatal Projection Neurons [PDF]
Journal of Neurophysiology, 2006 The ability of synaptically released GABA to facilitate action potential generation in striatal projection neurons was studied in brain slices using current-clamp, gramicidin-perforated whole cell recordings. Evoked GABAergic postsynaptic potentials (PSPs) were pharmacologically isolated with ionotropic glutamate receptor ...
Bracci, Enrico, Panzeri, Stefano
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Nature Communications, 2018 Long-range GABAergic hippocampal neurons project to cortical and subcortical areas, while vasoactive intestinal peptide (VIP+) interneurons can inhibit other GABAergic neurons.
Ruggiero Francavilla +9 more
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Subtypes of GABAergic neurons project axons in the neocortex [PDF]
Frontiers in Neuroanatomy, 2009 gamma-aminobutyric acid (GABA)ergic neurons in the neocortex have been regarded as interneurons and speculated to modulate the activity of neurons locally. Recently, however, several experiments revealed that neuronal nitric oxide synthase (nNOS)-positive GABAergic neurons project cortico-cortically with long axons.
Higo, Shigeyoshi +3 more
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Frontiers in Neuroanatomy, 2013 Despite the abundance of studies on γ-aminobutyric acid (GABA) ergic neuron distribution in the mouse developing spinal cord, no investigation has been devoted so far to their birthdates.
Jing eHuang +5 more
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Kv4 channel expression and kinetics in GABAergic and non-GABAergic rNST neurons
Journal of Neurophysiology, 2020 Here, we demonstrate that the transient outward K + current I A occurs in both GABAergic and non-GABAergic neurons via Kv4.3 channels in the rostral (gustatory) solitary nucleus. Although found in both cell types, I A
Z, Chen +7 more
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A MicroRNA-Based Gene-Targeting Tool for Virally Labeling Interneurons in the Rodent Cortex
Cell Reports, 2018 Summary: More specific and broadly applicable viral gene-targeting tools for labeling neuron subtypes are needed to advance neuroscience research, especially in rodent transgenic disease models and genetically intractable species.
Marianna K. Keaveney +5 more
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