Results 21 to 30 of about 786,405 (284)

Synaptic and intrinsic activation of GABAergic neurons in the cardiorespiratory brainstem network. [PDF]

PLoS ONE, 2012
GABAergic pathways in the brainstem play an essential role in respiratory rhythmogenesis and interactions between the respiratory and cardiovascular neuronal control networks.
Julie G Frank, David Mendelowitz
doaj   +1 more source

Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington’s disease

Nature Communications, 2020
Huntington’s disease (HD) is caused by Huntingtin (Htt) gene mutation resulting in the loss of striatal GABAergic neurons and motor functional deficits. We report here an in vivo cell conversion technology to reprogram striatal astrocytes into GABAergic ...
Zheng Wu, Matthew Parry, Xiao-Yi Hou, Minhui Liu, Hui Wang, Rachel E. Cain, Zifei Pei, Yuchen Chen, Zi-yuan Guo, Sambangi Abhijeet, Gong Chen   +10 more
semanticscholar   +1 more source

Live-Cell, Label-Free Identification of GABAergic and Non-GABAergic Neurons in Primary Cortical Cultures Using Micropatterned Surface. [PDF]

PLoS ONE, 2016
Excitatory and inhibitory neurons have distinct roles in cortical dynamics. Here we present a novel method for identifying inhibitory GABAergic neurons from non-GABAergic neurons, which are mostly excitatory glutamatergic neurons, in primary cortical ...
Sho Kono, Hideaki Yamamoto, Takatoshi Kushida, Ayumi Hirano-Iwata, Michio Niwano, Takashi Tanii   +5 more
doaj   +1 more source

Corticofugal GABAergic projection neurons in the mouse frontal cortex

Frontiers in Neuroanatomy, 2015
Cortical projection neurons are classified by hodology in corticocortical, commissural and corticofugal subtypes. Although cortical projection neurons had been regarded as only glutamatergic neurons, recently corticocortical GABAergic projection neurons ...
Ryohei eTomioka, Kenji eSakimura, Yuchio eYanagawa   +2 more
doaj   +1 more source

Turning a Negative into a Positive: Ascending GABAergic Control of Cortical Activation and Arousal

Frontiers in Neurology, 2015
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain. Recent technological advances have illuminated the role of GABAergic neurons in control of cortical arousal and sleep.
Ritchie Edward Brown, James Tim McKenna
doaj   +1 more source

Sodium salicylate suppresses GABAergic inhibitory activity in neurons of rodent dorsal raphe nucleus. [PDF]

PLoS ONE, 2015
Sodium salicylate (NaSal), a tinnitus inducing agent, can activate serotonergic (5-HTergic) neurons in the dorsal raphe nucleus (DRN) and can increase serotonin (5-HT) level in the inferior colliculus and the auditory cortex in rodents.
Yan Jin, Bin Luo, Yan-Yan Su, Xin-Xing Wang, Liang Chen, Ming Wang, Wei-Wen Wang, Lin Chen   +7 more
doaj   +1 more source

Ventral pallidal GABAergic neurons control wakefulness associated with motivation through the ventral tegmental pathway

Molecular Psychiatry, 2020
The ventral pallidum (VP) regulates motivation, drug addiction, and several behaviors that rely on heightened arousal. However, the role and underlying neural circuits of the VP in the control of wakefulness remain poorly understood. In the present study,
Yadong Li, Yan-Jia Luo, Wei Xu, Jing Ge, Y. Chérasse, Yi-Qun Wang, M. Lazarus, W. Qu, Zhi-Li Huang   +8 more
semanticscholar   +1 more source

Optogenetic activation of leptin- and glucose-regulated GABAergic neurons in dorsomedial hypothalamus promotes food intake via inhibitory synaptic transmission to paraventricular nucleus of hypothalamus

Molecular Metabolism, 2016
Objective: The dorsomedial hypothalamus (DMH) has been considered an orexigenic nucleus, since the DMH lesion reduced food intake and body weight and induced resistance to diet-induced obesity.
Zesemdorj Otgon-Uul, Shigetomo Suyama, Hiroshi Onodera, Toshihiko Yada   +3 more
doaj   +1 more source

Electroacupuncture inhibited carrageenan-induced pain aversion by activating GABAergic neurons in the ACC [PDF]

Mol Brain
Yichen Zhu, Haiju Sun, Siqi Xiao, Zui Shen, Xixiao Zhu, Yifang Wang, Xiaofen He, Boyi Liu, Yongliang Jiang, Yi Liang, Janqiao Fang, Xiaomei Shao   +11 more
openalex   +2 more sources

Long-range GABAergic connections distributed throughout the neocortex and their possible function

Frontiers in Neuroscience, 2010
Features and functions of long range GABAergic projection neurons in the developing cerebral cortex have been reported previously, although until now their significance in the adult cerebral cortex has remained uncertain. The septo-hippocampal circuit is
Nobuaki eTamamaki, Ryohei eTomioka
doaj   +1 more source