Results 31 to 40 of about 546,048 (293)

Glutamatergic and GABAergic neurons in the preoptic area of the hypothalamus play key roles in menopausal hot flashes

Frontiers in Aging Neuroscience, 2022
During menopause, when estrogen levels are low, abnormalities in the hypothalamic preoptic area (POA) of the thermoregulatory center can cause hot flashes. However, the involved neural population has not been identified.
Yanrong Sun, Hanfei Wang, Wenjuan Wang, Jiali Lu, Jinglin Zhang, Xiaofeng Luo, Liju Luan, Ke Wang, Jing Jia, Jing Jia, Junhao Yan, Junhao Yan, Lihua Qin   +12 more
doaj   +1 more source

GABAergic mechanism of propofol toxicity in immature neurons [PDF]

Journal of Neurosurgical Anesthesiology, 2006
Certain anesthetics exhibit neurotoxicity in the brains of immature but not mature animals. Gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the adult brain, is excitatory on immature neurons via its action at the GABAA receptor, due to a reversed transmembrane chloride gradient.
Sibel, Kahraman, Susan L, Zup, Margaret M, McCarthy, Gary, Fiskum   +3 more
openaire   +2 more sources

GABA signaling in the thalamus [PDF]

, 2004
Inhibition of neuronal activity in networks of the mammalian central nervous system is essential for all fundamental brain functions, ranging from perception, to consciousness, to action.
Frère, Samuel
core   +1 more source

Excitatory GABAergic Effects in Striatal Projection Neurons [PDF]

Journal of Neurophysiology, 2006
The ability of synaptically released GABA to facilitate action potential generation in striatal projection neurons was studied in brain slices using current-clamp, gramicidin-perforated whole cell recordings. Evoked GABAergic postsynaptic potentials (PSPs) were pharmacologically isolated with ionotropic glutamate receptor ...
Bracci, Enrico, Panzeri, Stefano
openaire   +2 more sources

Origins of Cortical GABAergic Neurons in the Cynomolgus Monkey [PDF]

Cerebral Cortex, 2008
In human most cortical gamma-aminobutyric acidergic (GABAergic) neurons are produced in the proliferative zones of the dorsal telencephalon in contrast to rodents. We report that in cynomolgus monkey fetuses cortical GABAergic neurons are generated in the proliferative zones of the dorsal telencephalon, in addition to the proliferative region of the ...
Petanjek, Zdravko, Berger, Brigite, Esclapez, Monique   +2 more
openaire   +3 more sources

Hypothalamic GABAergic Neurons: Their Roles in Health and Metabolic Diseases [PDF]

Frontiers in Endocrinology
Ying Wan, Ruimao Zheng, Bingwei Wang
exaly   +2 more sources

Kv4 channel expression and kinetics in GABAergic and non-GABAergic rNST neurons

Journal of Neurophysiology, 2020
Here, we demonstrate that the transient outward K+ current IA occurs in both GABAergic and non-GABAergic neurons via Kv4.3 channels in the rostral (gustatory) solitary nucleus. Although found in both cell types, IA is more prevalent in non-GABAergic cells; a larger conductance at more negative potentials leads to a greater impact on spike initiation ...
Z, Chen, A, Boxwell, C, Conte, T, Haas, A, Harley, D H, Terman, S P, Travers, J B, Travers   +7 more
openaire   +3 more sources

Chemogenetic and optogenetic stimulation of zona incerta GABAergic neurons ameliorates motor impairment in Parkinson’s disease

iScience, 2023
Summary: Parkinson’s disease (PD) is characterized by the degeneration of dopaminergic neurons in the substantia nigra and leads to progressive motor dysfunction.
Fenghua Chen, Junliang Qian, Zhongkai Cao, Ang Li, Juntao Cui, Limin Shi, Junxia Xie   +6 more
doaj   +1 more source

Ontogeny of synaptophysin and synaptoporin in the central nervous system [PDF]

, 1993
The expression of the synaptic vesicle antigens synaptophysin (SY) and synaptoporin (SO) was studied in the rat striatum, which contains a nearly homogeneous population of GABAergic neurons. In situ hybridization revealed high levels of SY transcripts in
Marquéze-Pouey, B., Betz, H., Knaus, P., Grabs, D., Ovtscharoff, W., Bergmann, M., Gratzl, Manfred, Reisert, I., M. Gratzl, H. Betz, W. Ovtscharoff, B. Marquèze-Pouey, P. Knaus, D. Grabs, I. Reisert, M. Bergmann   +15 more
core   +1 more source

Molecular development and laminar distribution of GABAergic interneurons of the cerebral cortex [PDF]

, 2011
GABAergic interneurons of the cerebral cortex represent one of the most diversified populations of cells of the Central Nervous System. It is well established that different subtypes of interneurons populate and integrate into the cortical layers, where
Lodato, Simona
core   +1 more source