Results 231 to 240 of about 60,800 (288)

Anticonvulsant Effects of Citronellal, Daidzin, and Phytol, Possibly Through GABAA Receptor and Voltage‐Gated Sodium Channel Interaction Pathways: In Vivo and In Silico Studies

Brain and Behavior, Volume 16, Issue 4, April 2026.
Citronellal, daidzin, and phytol exert significant anticonvulsant effects in a chick seizure model by enhancing GABAergic transmission and blocking voltage‐gated sodium channels, with combination therapies showing enhanced efficacy and a favorable safety profile.
Emon Mia, Md. Anisur Rahman, Md. Nasimul Haque Shipon, Moushumi Afroza Mou, Proma Mandal, Imam Hossen Rakib, Md. Abu Sayeed, Muhammad Torequl Islam, Md. Sakib Al Hasan, Mushtaq Ahmad Ansari   +9 more
wiley   +1 more source

Gabapentinoids-Induced Rhabdomyolysis/Myopathy: Clinical Characteristics, Management, Outcomes, and Critical Safety Alerts. [PDF]

J Pain Res
Liu M, Long M, Zhou X.
europepmc   +1 more source

A Disproportionality Analysis of Immune Checkpoint Inhibitors in Combination With Platinum‐Based Agents Using the FDA Adverse Event Reporting System Database

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Objective Immune checkpoint inhibitors (ICIs) combined with platinum‐based compounds are commonly used in the treatment of certain malignant tumors. This study aims to analyze adverse events (AEs) associated with the combination therapy of ICIs and platinum‐based compounds by using the FAERS database.
Boyi Liu, Wenchao Zhang, Ruizhe Huang, Dinwen Liu, Jiaxing Liu, Ao Han, Yike Li, Danna Chen   +7 more
wiley   +1 more source

Uremic Pruritus in Hemodialysis: Mechanisms, Burden, and Emerging Therapies. [PDF]

J Clin Med
Kljajić M, Parać E, Atić A, Bašić-Jukić N.   +3 more
europepmc   +1 more source

Challenges of Successive Dental Treatment Under General Anesthesia in a Patient With Drug Resistant Epilepsy: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Pediatric patients with uncontrolled tonic–clonic epilepsy and cognitive impairment present substantial challenges for dental pain management when cooperation is limited. We report a 13‐year‐old nonverbal male with lifelong generalized epilepsy, who underwent two comprehensive dental rehabilitations under general anesthesia.
Ahmad Al Malak, Mohammad Al Halabi, Yasmina El Masri, Farah Sarmout, Mohammad Hassoun, Ammar Rashid   +5 more
wiley   +1 more source

Effective Adolescent Hand CRPS Type 1 Treatment Using Ketamine, Gabapentin, and Supraclavicular Nerve Block Catheter-A Case Report. [PDF]

Children (Basel)
Medikondu H, Davit A, Visoiu M.
europepmc   +1 more source

Tarlov Cyst with Pelvic Extension Mimicking an Adnexal Mass: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Pelvic extension of sacral Tarlov cysts can closely resemble adnexal masses on ultrasound. When cystic pelvic lesions coexist with radicular pain or sitting intolerance, MRI is mandatory prior to gynecologic surgery. Conservative treatment is preferred unless neurological deterioration occurs.
Mahsa Karbasi, Alireza Motamedi, Armin Bakhshipour Roudsari, Esmaeil Gharepapagh, Mahsa Malekian, Sahar Rezaei   +5 more
wiley   +1 more source

Identifying predictors of neuropathic pain medication prescribing, adherence, and discontinuation: a systematic review and meta-analysis. [PDF]

Br J Anaesth
Koponen ME, Senaratne DNS, Hébert HL, Smith BH, Colvin LA.   +4 more
europepmc   +1 more source

Association of Pregabalin vs. Duloxetine with Cardiovascular Events: A Retrospective Cohort Study Among US Veterans With Chronic Musculoskeletal Pain

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1088-1094, April 2026.
Pregabalin and duloxetine are widely prescribed non‐opioid medications for chronic musculoskeletal pain. Pregabalin may increase the risk of heart failure, and duloxetine increases heart rate and blood pressure; however, little is known about their comparative cardiovascular safety.
Sachalee Campbell, Puran Nepal, Laura Daniel, Otis Wilson, Alyson L. Dickson, Jennifer Maizel, Katherine T. Murray, William D. Dupont, Adriana Hung, Wayne A. Ray, C. Michael Stein, Cecilia P. Chung   +11 more
wiley   +1 more source