Results 111 to 120 of about 6,786 (213)

Effectiveness of Gabapentinoids in Neuropathic Pain: A Single-Center Retrospective Study at a Specialized Institution in Mexico

Pharmacy
Background/Objectives: Gabapentinoids are first-line treatments for neuropathic pain (NP); however, real-world evidence regarding their safety and effectiveness in complex clinical populations remains limited.
Carlos Eduardo Estrada-De La Rosa, Felipe Alexis Avalos-Salgado, Nancy Evelyn Navarro-Ruiz, Erika Fabiola López-Villalobos, Roberto de Jesús Sandoval-Muñiz, Monserratt Abud-González, María Luisa Muñoz-Almaguer, Raymundo Escutia-Gutiérrez   +7 more
doaj   +1 more source

Mechanisms of the gabapentinoids and α2δ-1 calcium channel subunit in neuropathic pain [PDF]

, 2016
The gabapentinoid drugs gabapentin and pregabalin are key front-line therapies for various neuropathies of peripheral and central origin. Originally designed as analogs of GABA, the gabapentinoids bind to the α2δ-1 and α2δ-2 auxiliary subunits of calcium
Patel, RA, Dickenson, AH
core  

Comparison of median, unadjusted mean, and adjusted mean opioid agonist treatment (OAT) duration with concurrent prescription of benzodiazepines, z-drugs, and gabapentinoids, by OAT type.

, 2019
Comparison of median, unadjusted mean, and adjusted mean opioid agonist treatment (OAT) duration with concurrent prescription of benzodiazepines, z-drugs, and gabapentinoids, by OAT type.
John Strang (817558), John Macleod (119316), John Marsden (427925), Tim Millar (3598607), Colin Steer (159192), Rosie Cornish (3426482), Kate Tilling (213507), Matthew Hickman (83053)   +7 more
core   +1 more source

Comparison of log opioid agonist treatment (OAT) duration, plus interquartile range (IQR) of duration, for concurrent prescription of benzodiazepines, z-drugs, and gabapentinoids, by OAT type.

, 2019
Comparison of log opioid agonist treatment (OAT) duration, plus interquartile range (IQR) of duration, for concurrent prescription of benzodiazepines, z-drugs, and gabapentinoids, by OAT type.
John Strang (817558), John Macleod (119316), John Marsden (427925), Tim Millar (3598607), Colin Steer (159192), Rosie Cornish (3426482), Kate Tilling (213507), Matthew Hickman (83053)   +7 more
core   +1 more source

Abuse of gabapentinoids in individuals with substance use disorders

The abuse of gabapentinoids has increased rapidly, and death cases have been reported with increasing rates. This study examines the toxicological analysis data of substance abuse cases conducted after legal regulations were implemented in Türkiye.
Aslan, Rukiye, Saglam, Inci, Akgur, Serap Annette, Kurtulmus, Yusuf   +3 more
core   +1 more source

Association \u27Between Gabapentinoids on the Day of Colorectal Surgery and Adverse Postoperative Respiratory Outcomes

, 2019
OBJECTIVE: The aim of this study was to determine the association between gabapentinoids on the day of surgery and adverse postoperative outcomes in patients undergoing colorectal surgery in the United States.
Stefan, Mihaela, MD, Lindenauer, Peter
core   +1 more source

Perioperative use of gabapentinoids in France. Mismatch between clinical practice and scientific evidence

, 2018
International audienceBackground - Gabapentinoids have governmental health agency approval for "chronic neuropathic pain." Over the last decade, however, the perioperative prescription of gabapentinoids has become more popular among anaesthesiologists ...
Emmanuel Marret, Beloeil, Hélène, Hélène Beloeil, Martinez, Valeria, Carles, Michel, Marret, Emmanuel, Michel Carles, Valéria Martinez   +7 more
core   +1 more source

Prescribing Patterns and Off-Label Use of Gabapentinoid Agents at Dhulikhel Hospital, Nepal: A Cross-Sectional Study

Journal of Pain Research
Sumana Adhikari,1 Durga Bista,1 Rohit Shrestha,2 David Woods3 1Department of Pharmacy, Kathmandu University, Dhulikhel, Bagmati State, Nepal; 2Orthopedics and Traumatology Department, Dhulikhel Hospital, Dhulikhel, Bagmati State, Nepal; 3Faculty of ...
Adhikari S, Bista D, Shrestha R, Woods D
doaj  

Rates, Trends, and Determinants of Concurrent Prescription of Opioids, Other Central Nervous System Depressants, and Gabapentinoids in Ambulatory Care Settings - Evidence from National Dataset

, 2020
Purpose: Studies have analyzed the concomitant use of opioids, CNS depressants, and gabapentinoids (gabapentin and pregabalin) in the elderly and patients with chronic pain.
Rasu, Rafia, Howard, Meredith, Zalmai, Rana   +2 more
core  

The Impact of Gabapentinoids on Pain-Related Outcomes after Knee and Hip Surgery: A Systematic Review with Meta-Analysis of Randomized Controlled Trials

Background: Postoperative pain remains a significant challenge after knee and hip surgeries, two of the most frequently performed procedures, preventing patients from seeking timely surgical help.
Azamat Salamat, Mina Aubakirova, Dmitriy Viderman, Ramil Tankacheyev, Dastan Kaldybayev, Nurzhamal Sadir, Yerkin G. Abdildin   +6 more
core   +1 more source