Results 91 to 100 of about 6,345 (201)

Gabapentinoids In Pain Setting

open access: yesJournal of Pain & Relief, 2013
Surgical incision induces central and peripheral sensitization and hyperalgesia, and if remain untreated may lead to chronic postoperative pain after surgery. Antihyperalgesic drugs improve postoperative pain by preventing the development of central sensitization [1].
openaire   +1 more source

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3333-3353, October 2026.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili   +6 more
wiley   +1 more source

A highly aqueous HPLC-PDA method for the assay of gabapentin and pregabalin: applications in pharmaceutical analysis, dissolution testing, and forensic screening

open access: yesFrontiers in Chemistry
IntroductionGabapentinoids, particularly pregabalin (PGL) and gabapentin (GBP), are widely used for neurological and psychiatric conditions but are increasingly linked to misuse and forensic challenges.
Fatimah M. Alamri   +6 more
doaj   +1 more source

Rise of Pregabalin Poisoning and Abuse Cases in Serbia: A Ten-Year Retrospective Study

open access: yesInternational Journal of General Medicine, 2023
Marko Antunovic,1,2 Slavica Vucinic,1,2 Jelena Kotur-Stevuljevic,3 Kristijan Krstic,4 Jasmina Jovic-Stosic,1,2 Vesna Kilibarda,1,2 Natasa Perkovic-Vukcevic,1,2 Snezana Djordjevic1,2 1Medical Faculty Military Medical Academy, University of Defense ...
Antunovic M   +7 more
doaj  

Gabapentinoids in the perioperative period [PDF]

open access: yesAnesteziologie a intenzivní medicína, 2021
O Gimunová, J Zemanová
openaire   +1 more source

Prescribing Patterns of Gabapentinoids in Patients with Chronic Obstructive Pulmonary Disorder

open access: yesCOPD
In 2019, the U.S. Food and Drug Administration (FDA) issued a warning regarding the risk of serious respiratory depression in patients using gabapentin or pregabalin who have respiratory risk factors, including those with chronic obstructive pulmonary ...
Mollie Vergara   +10 more
doaj   +1 more source

Consumption patterns before and during the COVID-19 pandemic among patients admitted to inpatient drug detoxification treatment: Results of two cross-sectional surveys from 2018 and 2021

open access: yesFrontiers in Psychiatry
BackgroundThe lockdown measures during the SARS-CoV-2 pandemic could have influenced drug consumption patterns of persons with drug use disorder, especially due to a reduced availability of drugs, an increased consumption of sedating substances as a ...
Patrik Roser   +11 more
doaj   +1 more source

Wherefore Gabapentinoids? [PDF]

open access: yesAnesthesiology, 2016
Evan D, Kharasch, James C, Eisenach
openaire   +2 more sources

Comparative Effectiveness of Opioids and Opioid Substitutes on Pain and Health Related Quality of Life Among Cancer Survivors

open access: yesCancer Medicine
Introduction Chronic pain is a major but modifiable contributor to poor quality of life among long‐term cancer survivors. With growing concern over opioid‐related risks, gabapentinoids have emerged as a safer alternative, though evidence comparing their ...
Shirley K. Chan Sanchez   +4 more
doaj   +1 more source

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