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Gabapentinoids In Pain Setting
Surgical incision induces central and peripheral sensitization and hyperalgesia, and if remain untreated may lead to chronic postoperative pain after surgery. Antihyperalgesic drugs improve postoperative pain by preventing the development of central sensitization [1].
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Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili +6 more
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Patients' and prescribers' experiences of Gabapentinoids for ...
Rachel Routledge
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IntroductionGabapentinoids, particularly pregabalin (PGL) and gabapentin (GBP), are widely used for neurological and psychiatric conditions but are increasingly linked to misuse and forensic challenges.
Fatimah M. Alamri +6 more
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Rise of Pregabalin Poisoning and Abuse Cases in Serbia: A Ten-Year Retrospective Study
Marko Antunovic,1,2 Slavica Vucinic,1,2 Jelena Kotur-Stevuljevic,3 Kristijan Krstic,4 Jasmina Jovic-Stosic,1,2 Vesna Kilibarda,1,2 Natasa Perkovic-Vukcevic,1,2 Snezana Djordjevic1,2 1Medical Faculty Military Medical Academy, University of Defense ...
Antunovic M +7 more
doaj
Gabapentinoids in the perioperative period [PDF]
O Gimunová, J Zemanová
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Prescribing Patterns of Gabapentinoids in Patients with Chronic Obstructive Pulmonary Disorder
In 2019, the U.S. Food and Drug Administration (FDA) issued a warning regarding the risk of serious respiratory depression in patients using gabapentin or pregabalin who have respiratory risk factors, including those with chronic obstructive pulmonary ...
Mollie Vergara +10 more
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BackgroundThe lockdown measures during the SARS-CoV-2 pandemic could have influenced drug consumption patterns of persons with drug use disorder, especially due to a reduced availability of drugs, an increased consumption of sedating substances as a ...
Patrik Roser +11 more
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Wherefore Gabapentinoids? [PDF]
Evan D, Kharasch, James C, Eisenach
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Introduction Chronic pain is a major but modifiable contributor to poor quality of life among long‐term cancer survivors. With growing concern over opioid‐related risks, gabapentinoids have emerged as a safer alternative, though evidence comparing their ...
Shirley K. Chan Sanchez +4 more
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