Results 81 to 90 of about 6,786 (213)

Distinct effects of fibromyalgia pain, depression and anxiety on perception of affective touch and pain

The Journal of Physiology, EarlyView.
Abstract figure legend Patients with fibromyalgia (FM) and no‐pain controls completed questionnaire‐based ratings of chronic pain, childhood trauma, anxiety and depression. Brief touch stimuli were then administered, including slow brushing at the C‐tactile optimal velocity of 3 cm/s, deep oscillating pressure with a compression sleeve, roboticized ...
Benedetta Albinni, Marisa Zimmerman, Vincent Alasha, Jacob Ross, Lindsey Crankshaw, Sandy R. Hu, Nathaniel Schuster, Laura Case   +7 more
wiley   +1 more source

Use of gabapentin for neuropathic pain therapy: A view from perspective of evidence-based medicine

Фармация и фармакология (Пятигорск)
The aim of the study was to analyze the literature sources for pharmacodynamic and pharmacokinetic features of gabapentin, providing its use in patients with neuropathic pain, as well as a comparative evaluation of its efficacy and safety when used in ...
O. I. Butranova, S. K. Zyryanov
doaj   +1 more source

Systematic review: The relationship between gabapentinoids, etizolam, and drug related deaths in Scotland.

PLoS ONE
In recent years Scotland has been experiencing a disproportionally high number of drug related deaths compared to other European countries, causing significant individual, societal and economic burden.
Beata Ciesluk, Dr Greig Inglis, Adrian Parke, Lucy J Troup   +3 more
doaj   +1 more source

Patient Experiences of Chronic Low Back Pain: Development of a Conceptual Model Based on a Targeted Literature Review and Qualitative Patient Interviews

Musculoskeletal Care, Volume 24, Issue 4, December 2026.
ABSTRACT Purpose Chronic low back pain (CLBP) is a persistent, debilitating condition. The United States (US) Food and Drug Administration Patient‐Focused Drug Development Guidance recommends using patient‐reported outcome (PRO) measures to assess pain and function in clinical trials and document content validity of the measures based on patient ...
Ekin Seçinti, Brittany Klooster, Rebecca Robinson, Madison C. Bernstein, Madeline Tallarico, Kaitlin Chatterton, Adriana Voci, Daniella Olonilua, Samantha R. Linton, Leighann Litcher‐Kelly, Marcia M. Mellado Lagarde, Linda A. Wietecha, John Markman   +12 more
wiley   +1 more source

A meta-analysis on the use of gabapentinoids for the treatment of acute post-operative pain following total knee arthroplasty [PDF]

, 2016
Background: Total knee arthroplasty is a painful procedure, with approximately half of patients reporting severe pain during the early postoperative period.

core   +1 more source

Dependence on ultra-high doses of gabapentinoids: A case series

Indian Journal of Psychiatry
Gabapentinoids, including Gabapentin and Pregabalin, are increasingly misused, particularly by individuals with psychiatric comorbidities or prior substance use.
Arun Bansal, Bhavneesh Saini, Harman Rai, Jaskanwar S. Dhillon, Priyanka Bansal, Sumit Saini   +5 more
doaj   +1 more source

Characterization of the Lysophosphatidic Acid Receptor 5 Antagonist RLPA‐76 as a Novel Analgesic in Male Rats and Mice

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Clinically used analgesics such as gabapentinoids and opioids have limited efficacy and adverse effects like abuse liability, and there is a dire need for novel analgesics with improved safety profiles. Since lysophosphatidic acid can induce neuropathic pain in rodents, LPA receptor antagonists have been investigated as potential analgesics ...
Kristen L. Woodhouse, Maowei Wang, Sai Ganesh Balaji Venkata Anupindi, Olatunbosun Adeoke, Dehui Zhang, Yanan Zhang, Jun‐Xu Li   +6 more
wiley   +1 more source

COMPARATIVE EFFECTS OF GABAPENTINOIDS VS OPIOIDS ON FRAILTY AND PHYSICAL FUNCTION AMONG MEDICARE BENEFICIARIES [PDF]

The use of opioids in the treatment of chronic non-cancer pain has been the standard pharmacological option for many years. With the concern over the opioid epidemic, effective pain relief alternatives have been sought.
Westra, Jordan Russell 1990-
core   +2 more sources

Risk of Severe Exacerbation Associated with Gabapentinoid Use in Patients with Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study

COPD
Evidence on the risk of adverse respiratory outcomes associated with gabapentinoids in patients with chronic obstructive pulmonary disease (COPD) remains limited.
Omotayo Olaoye, Sophie Dell’Aniello, Pierre Ernst, Samy Suissa, Christel Renoux   +4 more
doaj   +1 more source

Chronic Scrotal Content Pain: A Practical Guide to Diagnosis and Management

Trends in Urology &Men's Health, Volume 17, Issue 6, December 2026.
ABSTRACT Chronic scrotal content pain (CSCP) is a common but often poorly understood condition that presents a significant diagnostic and therapeutic challenge. The broad differential diagnosis and frequent absence of an identifiable cause can lead to repeated investigations, delayed treatment and unnecessary surgery.
Mahin Chowdhury, Mohammad Arabiyat, Ibrahim Abuelbeh, Theodora Stasinou, Peter Grice, Vaibhav Modgil, Ian Pearce   +6 more
wiley   +1 more source