Results 61 to 70 of about 4,888 (188)

Use of gabapentin for neuropathic pain therapy: A view from perspective of evidence-based medicine

Фармация и фармакология (Пятигорск)
The aim of the study was to analyze the literature sources for pharmacodynamic and pharmacokinetic features of gabapentin, providing its use in patients with neuropathic pain, as well as a comparative evaluation of its efficacy and safety when used in ...
O. I. Butranova, S. K. Zyryanov
doaj   +1 more source

Modulation of pain by affective touch: effects of childhood trauma, depression, chronic pain, and spinal segment

The Journal of Physiology, EarlyView.
Abstract figure legend Patients with fibromyalgia and no‐pain controls completed questionnaire ratings of chronic pain, childhood trauma, anxiety and depression. During the first session a conditioned pain modulation task was administered, with heat pain applied via thermode and cold pain via cold water‐bath.
Benedetta Albinni, Marisa Zimmerman, Vincent Alasha, Jacob Ross, Lindsey Crankshaw, Emrys Jones, Jeffery Lewis, Sandy R. Hu, Nathaniel Schuster, Laura Case   +9 more
wiley   +1 more source

Systematic review: The relationship between gabapentinoids, etizolam, and drug related deaths in Scotland.

PLoS ONE
In recent years Scotland has been experiencing a disproportionally high number of drug related deaths compared to other European countries, causing significant individual, societal and economic burden.
Beata Ciesluk, Dr Greig Inglis, Adrian Parke, Lucy J Troup   +3 more
doaj   +1 more source

Distinct effects of fibromyalgia pain, depression and anxiety on perception of affective touch and pain

The Journal of Physiology, EarlyView.
Abstract figure legend Patients with fibromyalgia (FM) and no‐pain controls completed questionnaire‐based ratings of chronic pain, childhood trauma, anxiety and depression. Brief touch stimuli were then administered, including slow brushing at the C‐tactile optimal velocity of 3 cm/s, deep oscillating pressure with a compression sleeve, roboticized ...
Benedetta Albinni, Marisa Zimmerman, Vincent Alasha, Jacob Ross, Lindsey Crankshaw, Sandy R. Hu, Nathaniel Schuster, Laura Case   +7 more
wiley   +1 more source

Dependence on ultra-high doses of gabapentinoids: A case series

Indian Journal of Psychiatry
Gabapentinoids, including Gabapentin and Pregabalin, are increasingly misused, particularly by individuals with psychiatric comorbidities or prior substance use.
Arun Bansal, Bhavneesh Saini, Harman Rai, Jaskanwar S. Dhillon, Priyanka Bansal, Sumit Saini   +5 more
doaj   +1 more source

Plasma Lidocaine Concentrations During Intravenous Lidocaine Infusion Therapy in the Pediatric Population—A Scoping Review

Pediatric Anesthesia, Volume 36, Issue 9, Page 1041-1051, September 2026.
ABSTRACT Background Intravenous lidocaine therapy (IVLT) is often used in perioperative multimodal analgesia due to its analgesic, anti‐hyperalgesic, and anti‐inflammatory effects. In adults, IVLT doses of 1–2 mg/kg/h produce plasma concentrations of 1–2 μg/mL, within the presumed therapeutic range of 1–5 μg/mL.
McKenna Postles, Amanda Barton, Nicholas West, Gillian Lauder   +3 more
wiley   +1 more source

Risk of Severe Exacerbation Associated with Gabapentinoid Use in Patients with Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study

COPD
Evidence on the risk of adverse respiratory outcomes associated with gabapentinoids in patients with chronic obstructive pulmonary disease (COPD) remains limited.
Omotayo Olaoye, Sophie Dell’Aniello, Pierre Ernst, Samy Suissa, Christel Renoux   +4 more
doaj   +1 more source

Management of Pain in the Intensive Care Unit: A Nordic Survey

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 8, September 2026.
ABSTRACT Background Pain is common in intensive care unit (ICU) patients with up to one‐third experiencing pain at rest and even more during mobilization and clinical procedures. This survey aimed to explore physicians' attitudes and preferences regarding pain management in adult ICU patients in the Nordic countries.
Benedikte Kollerup Madsen, Morten Hylander Møller, Stine Estrup, Lone Musaeus Poulsen, Bodil Steen Rasmussen, Kirstine Sylvester Conradsen, Thomas Lass Klitgaard, Asger Granfeldt, Theis Skovsgaard Itenov, Hans Christian Thorsen Meyer, Signe Tellerup Nielsen, Susanne Andi Iversen, Klaus Tjelle Kristiansen, Morten Heiberg Bestle, Kirsten Møller, Peter Hasse Møller Sørensen, Jeppe Veien Nygaard, Kristian Elgaard, Morten Rune Blichfeldt‐Eckhardt, Ann Christine Waarkjær Olsen, Mette Pedersen, Henrik Westy Hoffmeyer, Peter Martin Hansen, Helle Bundgaard, Marcus Ølgaard Møller, Jarl Sigaard, Kim Zillo Rokamp, Anne Craveiro Brøchner, Christoffer Sølling, Mika Valtonen, Anna‐Maria Kuivalainen, Annukka Vahtera, Stepani Bendel, Martin I. Sigurdsson, Per Martin Bådstøløkken, Fredrik Sjövall, Ole Mathiesen, Lars Peter Kloster Andersen   +37 more
wiley   +1 more source

Community pharmacists’ engagement with Raqeeb platform: perceptions and implementation challenges toward controlled substance monitoring in Saudi Arabia

Frontiers in Pharmacology
IntroductionThe misuse of narcotic drugs and psychotropic substances (NDPS), especially gabapentinoids, poses a considerable public health concern in Saudi Arabia, leading to the establishment of the Raqeeb platform, a nationwide electronic platform for ...
Sultan M. Alshahrani
doaj   +1 more source

Central sensitization in patients with chronic pelvic pain resistant to hormonal therapy: A cross‐sectional study of prevalence and clinical correlates in a tertiary referral cohort

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 9, Page 1833-1839, September 2026.
In women with hormone‐resistant chronic pelvic pain, central sensitization is highly prevalent and independently associated with significant quality‐of‐life impairment and increased analgesic burden. These findings highlight the need for systematic screening of sensitization and trauma to optimize multidisciplinary management in specialized care ...
Hajar Alawadi, Marie Cid, Jérôme Delotte, Pierre‐Alexis Gauci   +3 more
wiley   +1 more source