Results 71 to 80 of about 43,371 (254)

Nano-sized cytochrome P450 3A4 inhibitors to block hepatic metabolism of docetaxel

International Journal of Nanomedicine, 2017
Marion Paolini,1,2 Laurence Poul,1 Céline Berjaud,1 Matthieu Germain,1 Audrey Darmon,1 Maxime Bergère,1 Agnès Pottier,1 Laurent Levy,1 Eric Vibert2 1Nanobiotix, Paris, 2UMR-S 1193 INSERM/Paris-Sud University, Centre Hépato ...
Paolini M, Poul L, Berjaud C, Germain M, Darmon A, Bergère M, Pottier A, Levy L, Vibert E   +8 more
doaj  

A Francisella mutant in lipid A carbohydrate modification elicits protective immunity.

PLoS Pathogens, 2008
Francisella tularensis (Ft) is a highly infectious gram-negative bacterium and the causative agent of the human disease tularemia. Ft is designated a class A select agent by the Centers for Disease Control and Prevention.
Duangjit Kanistanon, Adeline M Hajjar, Mark R Pelletier, Larry A Gallagher, Thomas Kalhorn, Scott A Shaffer, David R Goodlett, Laurence Rohmer, Mitchell J Brittnacher, Shawn J Skerrett, Robert K Ernst   +10 more
doaj   +1 more source

Purification and properties of a plant Agglutinin [PDF]

, 1958
Thesis (M.A.)--Boston UniversityThis study involved work with extracts of the seeds of Bauhinia purpurea alba, in which an N specific lectin was found by Mäkelä (37) and Boyd and McMaster (16). There were two main purposes in mind.
Everhart, Donald Lee
core   +1 more source

Biological Signatures of Inflammation Biomarkers Identified Using Data Reduction Methods in Adult Population: A Scoping Review Protocol

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Chronic inflammation contributes to various chronic diseases, emphasizing the need for reliable biomarkers for early detection and understanding its causes. Measuring chronic inflammation poses challenges since most biomarkers are influenced by both acute and chronic states and recent exposures.
Gary Sánchez‐Gordón, Elena Plans‐Beriso, Cristina Barahona‐López, Berta Anta, Oscar Millet, Pablo Fernández‐Navarro, Nerea Fernández de Larrea‐Baz, Adela Castelló‐Pastor   +7 more
wiley   +1 more source

New sialic acid-containing sulfolipid: “ungulic acid”

Journal of Lipid Research, 1969
Human epidermis, hair, nails, and kidney as well as bovine and horses' hooves were found to contain a lipid fraction, which on thin-layer chromatography migrated slightly ahead of the cerebroside sulfate esters and gave the color reaction specific for ...
E. Leikola, Elna Nieminen, Anna-Maija Teppo   +2 more
doaj   +1 more source

The binding of glycosaminoglycans to peptides : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 1994
The overall aim this study was to examine the possibility of using immobilised polypeptide chains to fractionate/separate Glycosaminoglycans (GAG's) from mixtures. Initially individual samples of three GAG classes (chondroitin sulphate, dermatan sulphate
Taylor, Grant John
core  

Specific radioactive labeling of terminal N-acetylgalactosamine of glycosphingolipids by the galactose oxidase–sodium borohydride method

Journal of Lipid Research, 1972
The galactose oxidase–sodium borohydride method was used to specifically label the terminal N-acetylgalactosamine of three glycosphingolipids, Gm2-ganglioside, asialo-Gm2-ganglioside, and globoside.
Yoshiyuki Suzuki, Kunihiko Suzuki
doaj   +1 more source

Amelioration of galactosamine-induced nephrotoxicity by a protein isolated from the leaves of the herb, L [PDF]

, 2007
Background Galactosamine (GalN), an established experimental toxin, mainly causes liver injury via the generation of free radicals and depletion of UTP nucleotides. Renal failure is often associated with end stage liver damage.
Mahua Sinha, Prasenjit Manna, Parames C Sil, Z Kmiec, D Keppler, D Keppler, AJ Makin, SK EI-Mofty, P Javle, M Epstein, R Anand, HL Hu, M Mangeney-Andreani, KH Han, K Sugiyama, MA Gyamfi, HK Lim, H Farghali, JS Kang, CK Chauhan, IA Donatus, PS Venkateswaran, DW Unander, M Chatterjee, M Chatterjee, R Bhattacharjee, A Bharani, K Karthikeyan, P Manna, BR Choudhuri, A Ghosh, K Sarkar, A Ghosh, A Ghosh, K Sarkar, K Sarkar, MM Bradford, RW Bonses, CL Crocker, H Esterbauer, M Nishikimi, P Kakkar, J Bonaventura, WH Habig, IK Smith, GL Ellman, PJ Hissin, J Sedlak, A Quintero, O Sire, F Guarner, JD Firth, S Uchida, H Sakamoto, K Moore, SM Khan, PS Oh, SJ Lee, AY Tsoi   +58 more
core   +2 more sources

RNA‐Based Therapies for Inherited Metabolic Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri, Sonam Gurung, Roopkatha Ghosh, Philippa B. Mills, Julien Baruteau, Haiyan Zhou   +5 more
wiley   +1 more source

The Protection of Midazolam Against Immune Mediated Liver Injury Induced by Lipopolysaccharide and Galactosamine in Mice

Frontiers in Pharmacology, 2019
Objectives: Liver macrophages agitated by Lipopolysaccharide (LPS) can enhance immuno-inflammatory responses in the liver which mediate liver injury and result in dysfunction.
Jian Li, Jian Li, Jian Li, Hong Tan, Hong Tan, Xiaona Zhou, Xiaona Zhou, Chunpan Zhang, Chunpan Zhang, Chunpan Zhang, Hua Jin, Hua Jin, Hua Jin, Yue Tian, Yue Tian, Yue Tian, Xinyan Zhao, Xinyan Zhao, Xinmin Li, Xinmin Li, Xinmin Li, Xuelian Sun, Xuelian Sun, Meili Duan, Meili Duan, Meili Duan, Dong Zhang, Dong Zhang, Dong Zhang, Dong Zhang   +29 more
doaj   +1 more source