Results 51 to 60 of about 26,061 (186)

A Francisella mutant in lipid A carbohydrate modification elicits protective immunity.

open access: yesPLoS Pathogens, 2008
Francisella tularensis (Ft) is a highly infectious gram-negative bacterium and the causative agent of the human disease tularemia. Ft is designated a class A select agent by the Centers for Disease Control and Prevention.
Duangjit Kanistanon   +10 more
doaj   +1 more source

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

open access: yesMass Spectrometry Reviews, Volume 45, Issue 4, Page 829-850, July/August 2026.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song   +3 more
wiley   +1 more source

New sialic acid-containing sulfolipid: “ungulic acid”

open access: yesJournal of Lipid Research, 1969
Human epidermis, hair, nails, and kidney as well as bovine and horses' hooves were found to contain a lipid fraction, which on thin-layer chromatography migrated slightly ahead of the cerebroside sulfate esters and gave the color reaction specific for ...
E. Leikola   +2 more
doaj   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen   +6 more
wiley   +1 more source

Specific radioactive labeling of terminal N-acetylgalactosamine of glycosphingolipids by the galactose oxidase–sodium borohydride method

open access: yesJournal of Lipid Research, 1972
The galactose oxidase–sodium borohydride method was used to specifically label the terminal N-acetylgalactosamine of three glycosphingolipids, Gm2-ganglioside, asialo-Gm2-ganglioside, and globoside.
Yoshiyuki Suzuki, Kunihiko Suzuki
doaj   +1 more source

Metabolic Dysfunction‐Associated Fatty Liver Disease: From Pathogenesis to Treatment

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Extracellular vesicles play a crucial role in interorgan crosstalk of adipose–liver and gut–liver axes and hold potential as therapeutic targets and drug delivery systems for metabolic dysfunction‐associated fatty liver disease (MAFLD). Abbreviations: AT: adipose tissue; EVs: extracellular vesicles; HL: healthy liver; NAFL: nonalcoholic fatty liver ...
Zhifu Cui   +5 more
wiley   +1 more source

Naltrexone Protects Against Lipopolysaccharide/D-Galactosamine–Induced Hepatitis in Mice

open access: yesJournal of Pharmacological Sciences, 2008
Naltrexone, an opioid receptor antagonist, has been claimed to have anti-inflammatory and immunomodulatory effects both in vitro and in vivo.
Chien-Chuan Wang   +5 more
doaj   +1 more source

Luzindole attenuates LPS/-galactosamine-induced acute hepatitis in mice

open access: yesInnate Immunity, 2020
Melatonin is a well-documented hormone that plays central roles in the regulation of sleep–wake cycles. There is cumulative evidence to suggest that melatonin is also a pleiotropic regulator of inflammation, and luzindole has been widely used as a ...
Yisheng Luo   +6 more
doaj   +1 more source

Atherosclerosis: Molecular Pathogenesis and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Molecular factors, like transforming growth factor beta (TGF‐β), mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase (PI3K), or cyclin‐dependent kinases (CDKs) 5 and 9, are essential modulators of atherosclerotic lesions. The novel, promising strategies for atherosclerosis treatment include therapies based on small interfering RNA (siRNA)
Jonatan Kaszubski   +3 more
wiley   +1 more source

ANTIOXIDATIVE EFFECT OF EPIGALLOCATECHIN GALLATE AGAINST D-GALACTOSAMINE-INDUCED INJURY IN PRIMARY CULTURE OF RAT HEPATOCYTES

open access: yesActa Medica, 2014
Literature data support that green tea and its major component epigallocatechin gallate (EGCG) have powerful antioxidant effects. Contrary, hepatotoxicity can be induced by high-dose EGCG. The timing of exposure to green tea in relation to administration
Alena Moravcová   +4 more
doaj   +1 more source

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