Results 51 to 60 of about 41,097 (233)

Long‐term warming drives mineral‐associated organic carbon accumulation on the Tibetan Plateau

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Global warming affects both plant growth and soil microbial decomposition, creating uncertainty for the storage and persistence of soil organic carbon (SOC) stock. Limited decomposition rates often characterise cold alpine ecosystems.
Siyi Sun, Jiacong Zhou, Carsten W. Mueller, Manuel Delgado‐Baquerizo, Yixuan Zhang, Kees Jan van Groenigen, Andrew Nottingham, Wolfram Buss, Xin Chen, Sergio Velasco Ayuso, Jeppe Aagaard Kristensen, Ying Ma, Shuo Liu, Fabián Scholz, Wolfgang Wanek, Jørgen Eivind Olesen, Junji Cao, Ji Chen   +17 more
wiley   +1 more source

The Model of D-Galactosamine-Induced Injury of Rat Hepatocytes in Primary Culture

Acta Medica, 2006
D-galactosamine (GalN) is a highly selective hepatotoxin that causes liver damage similar to human viral hepatitis via depletion of uridine nucleotides, which subsequently diminishes synthesis of RNA and proteins. Model of galactosamine hepatotoxicity is
Otto Kučera, Halka Lotková, Roman Kanďár, Renata Héžová, Vladimíra Mužáková, Zuzana Červinková   +5 more
doaj   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Expression pattern of glycoconjugates in the Bidderian and ovarian follicles of the Brazilian toad Bufo ictericus analyzed by lectin histochemistry

Brazilian Journal of Biology
The Bidder's organ and ovary of the Brazilian toad Bufo ictericus were studied by light microscopy, using hematoxylin-eosin (HE) and periodic acid Schiff (PAS) staining.
C. F. Farias, R. A. Azevedo, L. Brito-Gitirana   +2 more
doaj   +1 more source

The effect of cholinesterase inhibition on liver dysfunction in experimental acute liver failure

Egyptian Journal of Critical Care Medicine, 2013
Introduction: Acute liver failure (ALF), like sepsis, is associated with an overwhelming activation of the immune response in which hepatic and circulating inflammatory cytokines play a pivotal role.
Rasha S. Bondok, Mona A. Ahmed, Nevine Bahaa E. Soliman, Mona H. El-Shokry, Rania M. Ali, Hala F. Fahmy, Mohamed S. Eldin   +6 more
doaj   +1 more source

Isolated Kidney Transplant in Primary Hyperoxaluria‐1 Enabled by Small Interfering RNA (siRNA) Therapy. Is It Time for Change? Case Report and Review of the Literature

Pediatric Transplantation, Volume 30, Issue 5, May 2026.
ABSTRACT Background Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder characterized by excessive oxalate production that leads to nephrocalcinosis or nephrolithiasis and progressive kidney failure, associated with systemic oxalosis that is not reversed by dialysis. Pharmacological treatment is limited.
Shameer M. Habeeb, Eva Simkova, Samhar Al‐Akash, Hazem S. Awad, Haneen Yamin, Loai A. Eid, Watfa S. Aldhaheri, Waldo Concepcion, Martin Bitzan   +8 more
wiley   +1 more source

Dual endothelin-converting enzyme/neutral endopeptidase blockade in rats with D-galactosamine-induced liver failure

European Journal of Medical Research, 2011
Secondary activation of the endothelin system is thought to be involved in toxic liver injury. This study tested the hypothesis that dual endothelin-converting enzyme / neutral endopeptidase blockade might be able to attenuate acute toxic liver injury ...
Hocher B, Heiden S, von Websky K, Rahnenführer J, Kalk P, Pfab T   +5 more
doaj   +1 more source

Evaluation of Brown Micro-Algae Synergies With Low Dose -Radiation Against Chronic Hepatitis Induced by D-Galactosamine in Rats

Dose-Response, 2023
Introduction Hepatic inflammation is considered key driver of hepatic tissue impairment.We aimed to explore the interaction of Halamphora coffeaeformis ( Amph .) with low dose ionizing γ radiation ( γ R) exposure against D-galactosamine (D-GaIN)-induced ...
Salma Elsaman, Sawsan M. Elsonbaty, Fatma S. M. Moawed, Marwa G. A. Hegazy   +3 more
doaj   +1 more source

D-Galactosamine Causes Liver Injury Synergistically with Lipopolysaccharide but not Zymosan in Chicks

The Journal of Poultry Science, 2023
The pathogen-associated molecular patterns (PAMPs) lipopolysaccharide (LPS) and zymosan, derived from gram-negative bacteria and fungi, respectively, activate the innate immune system and cause injury to multiple organs, including the liver and intestine,
Maki Takahashi, Akira Senga, Kei Teraoka, Sakirul Khan, Ryosuke Makino, Mark A. Cline, Tetsuya Tachibana   +6 more
doaj   +1 more source

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

Advanced Science, Volume 13, Issue 21, 13 April 2026.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider, Alexander Fuchs, Michael Fichter, Vanessa Bolduan, Jenny Schunke, Özlem Akilli, Nádia C. Correia, Yannick Ehlers, Christian Czysch, Pia Winterwerber, Eliana Stanganello, Barbara Schrörs, Mustafa Diken, Christoph Eckert, Shusruto Rishik, Andreas Keller, Jörn M. Schattenberg, Stephan Grabbe, Matthias Bros, Lutz Nuhn, Leonard Kaps   +20 more
wiley   +1 more source