Sialylation patterns in cerebral amyloid angiopathy
This study is the first to localize and evaluate sialylation modifications in the context of Alzheimer's Disease and Cerebral Amyloid Angiopathy, revealing a unique disease‐specific increase in intravascular sialylation. Abstract Glycosylation is the most common form of post‐translational modification in the brain and becomes significantly altered in ...
Caitlyn Fastenau +8 more
wiley +1 more source
A bacterial nutrition strategy for plant disease control. [PDF]
Wang S +23 more
europepmc +1 more source
A century of theories of balancing selection
ABSTRACT Traits that affect organismal fitness are often highly genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature – after all – ‘selects’ the best genotypes at the expense of those that fall short.
Filip Ruzicka +10 more
wiley +1 more source
Comparative metabolomic analysis of leaves and kernels in wild type and <i>Zmsps2</i> mutant. [PDF]
Lin J +5 more
europepmc +1 more source
Uridine Diphosphate Galactose 4-Epimerase from Yeast
Robert A. Darrow, Robert Rodstrom
openalex +1 more source
The return of metabolism: biochemistry and physiology of glycolysis
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
Decanoic acid, an MCT dietary component, alleviates cognitive impairment, cellular senescence, and promotes autophagy in accelerated aging and neurotoxic mouse models induced by chronic administration of D-galactose and D-galactose/AlCl<sub>3</sub>. [PDF]
Jain S, Vohora D.
europepmc +1 more source
FAM20B Related Skeletal Dysplasia: Expanding the Prenatal Phenotype
FAM20B encodes glycosaminoglycan xylosylkinase, a key enzyme in proteoglycan biosynthesis. We report compound heterozygous FAM20B variants causing severe, lethal skeletal dysplasia in three fetuses from two pregnancies. Disrupted glycosaminoglycan chain formation leads to abnormal cartilage and bone development, illustrating the essential role of ...
Arda Arduç +8 more
wiley +1 more source
Description of 15 novel species within genus <i>Janthinobacterium</i> isolated from glaciers. [PDF]
Yang LL, Xin YH, Liu Q.
europepmc +1 more source

