Results 51 to 60 of about 274,419 (351)

Bacterial Adhesion of Streptococcus suis to Host Cells and Its Inhibition by Carbohydrate Ligands

Biology, 2013
Streptococcus suis is a Gram-positive bacterium, which causes sepsis and meningitis in pigs and humans. This review examines the role of known S. suis virulence factors in adhesion and S.
Sauli Haataja, Jukka Finne, Vuokko Loimaranta, Roland J. Pieters, Ulf J. Nilsson, Annika Kouki   +5 more
doaj   +1 more source

Drug-Loaded Silver Nanoparticles—A Tool for Delivery of a Mebeverine Precursor in Inflammatory Bowel Diseases Treatment

Biomedicines, 2023
Chronic, multifactorial illnesses of the gastrointestinal tract include inflammatory bowel diseases. One of the greatest methods for regulated medicine administration in a particular region of inflammation is the nanoparticle system. Silver nanoparticles
Mina Todorova, Miglena Milusheva, Lidia Kaynarova, Deyana Georgieva, Vassil Delchev, Stanislava Simeonova, Bissera Pilicheva, Stoyanka Nikolova   +7 more
doaj   +1 more source

Galactose:PEGamine coated gold nanoparticles adhere to filopodia and cause extrinsic apoptosis [PDF]

, 2018
Ultra-small gold nanoparticles, surface functionalised with a 50:50 ratio of a thiolated α-Galactose derivative and a thiolated hexaethylene glycol amine, are toxic to HSC-3 oral squamous carcinoma cells.
Espinosa Garcia, Cristina, Golding, Jon, Tzelepi, Konstantina, Williams, Phil   +3 more
core   +1 more source

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

Advanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui, Feifei Zhou, Yuan Luo, Tao Ouyang, Huiwu Zhang, Songmiao Cheng, Qiang Li, Xu Jiang, Yingying Yu, Yicheng Wang, Hong Ming   +10 more
wiley   +1 more source

Beyond the Dilemmas: Design of PLA-PEG Assemblies Based on pH-Reversible Boronic Ester for the Synchronous PEG De-Shielding and Ligand Presentation to Hepatocytes

Applied Sciences, 2022
A new polymeric construct is proposed as a starting material for a liver-targeted delivery system in the present communication. The polymeric material has been designed to be sensitive to pH variations and potentially loaded with hydrophobic antitumoral ...
Carla Sardo, Carmela Tommasino, Giulia Auriemma, Tiziana Esposito, Rita Patrizia Aquino   +4 more
doaj   +1 more source

Delayed Anaphylaxis Involving IgE to Galactose-alpha-1,3-galactose [PDF]

Current Allergy and Asthma Reports, 2015
Hypersensitivity in the allergic setting refers to immune reactions, stimulated by soluble antigens that can be rapidly progressing and, in the case of anaphylaxis, are occasionally fatal. As the number of known exposures associated with anaphylaxis is limited, identification of novel causative agents is important in facilitating both education and ...
Thomas A E, Platts-Mills, Alexander J, Schuyler, Alice E W, Hoyt, Scott P, Commins   +3 more
openaire   +2 more sources

Unveiling the metabolic fate of monosaccharides in cell membranes with glycomic and glycoproteomic analyses. [PDF]

, 2019
Cell membrane protein glycosylation is dependent on the metabolic state of the cell as well as exogenous nutrients available. Although the metabolism and interconversion of monosaccharides have been well-studied, their incorporation into cell surface ...
Cheng, Zhi, Lebrilla, Carlito B, Li, Qiongyu, Park, Dayoung, Wong, Maurice, Xu, Gege   +5 more
core  

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Genome-wide analysis of the UDP-glucose dehydrogenase gene family in Arabidopsis, a key enzyme for matrix polysaccharides in cell walls [PDF]

, 2007
Arabidopsis cell walls contain large amounts of pectins and hemicelluloses, which are predominantly synthesized via the common precursor UDP-glucuronic acid.
Klinghammer, Michaela, Tenhaken, Raimund
core   +1 more source

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source