Results 211 to 220 of about 14,424 (294)

Local Growth Hormone Facilitates Aging of the Colon Epithelial Microenvironment

Aging Cell, EarlyView.
Local growth hormone (GH) is expressed and secreted by senescent cells in the aging human colon. GH triggers epithelial‐to‐mesenchymal transition and activates colon cell motility by regulating extracellular matrix proteins, inducing cytoskeleton rearrangement and altering cell motility protein phosphorylation.
Vera Chesnokova, Svetlana Zonis, Richard Ainsworth, Tugce Apaydin, Christian Wong Valencia, Elora C. Greiner, Robert Barrett, Arminja N. Kettenbach, Shlomo Melmed   +8 more
wiley   +1 more source

Enhancing β-Galactosidase Performance for Galactooligosaccharides Preparation via Strategic Glucose Re-Tunneling. [PDF]

Int J Mol Sci
Zhao J, Niu D, Liu J, Jin Z, Mchunu NP, Singh S, Wang Z.   +6 more
europepmc   +1 more source

Evidence for Nonidentical Chains in the β-Galactosidase of Escherichia coli K12

, 1965
Edward Steers, Gary R. Craven, Christian B. Anfinsen, J. L. Bethune   +3 more
openalex   +1 more source

TSP50 in Neural Stem Cells Regulates Aging‐Related Cognitive Decline and Neuroinflammation by Altering the Gut Microbiota

Aging Cell, EarlyView.
TSP50 expression declines in the hippocampus of aged humans and mice. TSP50 deficiency in NSCs accelerates mouse aging, causing cognitive impairments and neuroinflammation. Restoring gut microbiota via FMT and TSP50 overexpression alleviates these phenotypes. Our study shows TSP50's critical role in aging and gut microbiota as a key mediator.
Xiaoli Li, Yuecong Chen, Zhuoyi Gao, Xiaoling Liu, Zhenbo Song, Feng Gao, Shuyue Wang, Chunlei Yu, Luguo Sun, Yanxin Huang, Lihua Zheng, Guannan Wang, Ying Sun, Jiawei Li, Xiaoguang Yang, Yongli Bao   +15 more
wiley   +1 more source

Silencing of the Alkaline α-Galactosidase Gene <i>CsAGA1</i> Impairs Root and Gall Development in Cucumber upon <i>Meloidogyne incognita</i> Infection. [PDF]

Int J Mol Sci
Ji T, Wang X, Wang X, Gao L, Tian Y, Ma S.   +5 more
europepmc   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

Metabolic insights of lactic acid bacteria in reducing off-flavors and antinutrients in plant-based fermented dairy alternatives. [PDF]

Compr Rev Food Sci Food Saf
Molina GES, Ras G, da Silva DF, Duedahl-Olesen L, Hansen EB, Bang-Berthelsen CH.   +5 more
europepmc   +1 more source

Regulation of β-Galactosidase Synthesis in Escherichia coli by Cyclic Adenosine 3′,5′-Monophosphate

, 1968
Robert L. Perlman, Ira Pastan
openalex   +1 more source

PRRX2 Regulates GLI2 to Promote Proliferation, Invasion, and Metastasis by Inhibiting Senescence via Hedgehog Signaling

Cancer Science, EarlyView.
PRRX2 is highly expressed in pancreatic cancer and correlates with patient prognosis. PRRX2 promotes pancreatic cancer cell proliferation, invasion, and metastasis, and inhibits pancreatic cancer cell senescence. PRRX2 transcriptionally regulates GLI2 and activates the Hedgehog pathway.
Wei Huang, Feiqiang xu, Jichuan xu, Gang Quan, Shihang zhang, Mengmeng guo, Feng xiao, Jianxin jiang   +7 more
wiley   +1 more source

Safety evaluation of an extension of use of the food enzyme β-galactosidase from the genetically modified <i>Aspergillus niger</i> strain TOL. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Cavanna D, Liu Y.   +14 more
europepmc   +1 more source