Results 211 to 220 of about 18,981 (340)

Senescent Macrophages Promote Age‐Related Revascularization Impairment by Increasing Antiangiogenic VEGF‐A165B Expression

open access: yesAging Cell, EarlyView.
The underlying mechanisms of age‐related revascularization impairment are not clear. Our research firstly identified that macrophages were more senescent in the ischemic skeletal muscle of old mice and senescent macrophages could inhibit revascularization.
Minghong Chen   +7 more
wiley   +1 more source

Recombinant production of Paenibacillus wynnii β-galactosidase with Komagataella phaffii. [PDF]

open access: yesMicrob Cell Fact
Bechtel A   +5 more
europepmc   +1 more source

Identifying PDAP1 as a Biological Target on Human Longevity: Integration of Mendelian Randomization, Cohort, and Cell Experiments Validation Study

open access: yesAging Cell, EarlyView.
Integration of multi‐omics analyses reveals PDAP1 as one of the key regulators of longevity and aging. Mendelian randomization, colocalization, prospective studies, and in vitro experiments highlight PDAP1's effects on mortality, lifespan, and cellular senescence.
Tianzhichao Hou   +18 more
wiley   +1 more source

Mucin-driven ecological interactions in an in vitro synthetic community of human gut microbes. [PDF]

open access: yesGlycobiology
Berkhout MD   +5 more
europepmc   +1 more source

Identification of Senomorphic miRNAs in Embryonic Progenitor and Adult Stem Cell‐Derived Extracellular Vesicles

open access: yesAging Cell, EarlyView.
A senomorphic miRNA cocktail (E5), consisting of miR‐181a‐5p, miR‐92a‐3p, miR‐21‐5p, and miR‐186‐5p, was identified from a pool of miRNAs enriched in extracellular vesicles (EVs) derived from multiple functional human stem cell types. E5 reduces senescence and SASP markers both in cell culture and in aged mice.
Tianpeng Zhang   +11 more
wiley   +1 more source

Identification and Characterization of a New Thermophilic κ-Carrageenan Sulfatase. [PDF]

open access: yesJ Agric Food Chem
Rhein-Knudsen N   +9 more
europepmc   +1 more source

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