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Evaluation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Analysis of Glucosylceramide and Galactosylceramide Isoforms in Cerebrospinal Fluid of Parkinson's Disease Patients. [PDF]

Anal Chem
Castillo-Ribelles L, Arranz-Amo JA, Hernández-Vara J, Samaniego-Toro D, Enriquez-Calzada S, Pozo SL, Camprodon-Gomez M, Laguna A, Arrúe-Gonzalo M, Ferrer R, Martinez-Vicente M, Martinez-Vicente M, Carnicer-Caceres C.   +12 more
europepmc   +1 more source

A divergent synthesis of α-galactosylceramide analogues

, 2012
Guillaume, Joren, Van Calenbergh, Serge
openaire   +2 more sources

Comprehensive Lipidomic Characterization of Human Blood by High-Throughput UHPSFC/MS using Bioinert Column and Modified MTBE Extraction

Peroutková P, Jirásko R, Taylor A, Holčapek M, Peterka O.   +4 more
europepmc   +1 more source

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Immunostimulatory activities of mono- or diglycosylated α-galactosylceramides

Bioorganic and Medicinal Chemistry, 1997
We examined the effects of 2"- or 3"-monoglycosylated alpha-galactosylceramides (alpha-GalCers) and 2",3"-diglycosylated alpha-GalCers on allogeneic MLR and the proliferation of murine spleen cells. It was found that their ceramide portions greatly affect their immunostimulatory activities, and that the 3"-hydroxyl group plays a more important role in ...
Kazuhiro Motoki, Yasuhiko Koezuka, Y Koezuka   +2 more
exaly   +4 more sources

Radioprotective effects of α-galactosylceramides

Bioorganic and Medicinal Chemistry Letters, 1995
Abstract We examined the life-span-prolonging effects of five kinds of α-Galactosylceramides (α-GalCers) on mice irradiated with lethal dose (9 Gy) of X ray, and found that they show strong radioprotective activities even when they are administered to mice after the irradiation.
Kazuhiro Motoki, Yasuhiko Koezuka, Hideaki Fukushima   +2 more
exaly   +3 more sources

Tegument galactosylceramides of the cestode Spirometra mansonoides.

Molecular and Biochemical Parasitology, 1987
The brush border-like surface of the tegument of the adult and the plerocercoid larva of a pseudophyllidean cestode, Spirometra mansonoides, has been shown to contain hydroxylated galactosylceramides. D-Galactosyl-N-(2-D-hydroxyoctadecanoyl)-D-phytosphingosine, D-galactosyl-N-(2-D-hydroxyoctadecanoyl)-D-dihydrosphingosine and D-galactosyl-N ...
B. Singh, C. Costello, S. Levery, R. Walenga, D. Beach, J. Mueller, G. Holz   +6 more
semanticscholar   +3 more sources

Galactosylceramides in human plasma.

American Journal of Clinical Pathology, 1973
The purpose of this investigation was to establish levels of cerebrosides in human plasma as a guide in investigating cerebroside levels in destructive and demyelinating central nervous system disorders. As an increase in plasma galactosylceramide may accompany myelin breakdown, this test may serve as a means of monitoring diseases such as multiple ...
H. Wells, M. Jones
semanticscholar   +3 more sources

Optical Control of Cytokine Production Using Photoswitchable Galactosylceramides.

Chemistry – A European Journal, 2019
Alpha-Galactosylceramides are glycosphingolipids that show promise in cancer immunotherapy. After presentation by CD1d they activate natural killer T cells (NKT), which results in the production of a variety of pro-inflammatory and immunomodulatory ...
Nina Hartrampf, T. Seki, A. Baumann, P. Watson, Nynke A. Vepřek, Belinda E. Hetzler, A. Hoffmann‐Röder, M. Tsuji, D. Trauner   +8 more
semanticscholar   +3 more sources

Synthesis of galactosylphytosphingosine and galactosylceramides containing phytosphingosine.

Chemistry and Physics of Lipids, 1974
Abstract Phytosphingosine prepared from the yeast Hansenula ciferrii was used for synthesis of galactosphingolipids. Glycosidation of N -dichloroacetyl and 3,4-di- O -benzoyl protected phytosphingosine was performed with acetobromogalactose in the presence of mercury cyanide.
I. Pascher
semanticscholar   +3 more sources

Molecular Characterization and Anti-inflammatory Activity of Galactosylglycerides and Galactosylceramides from the Microalga Isochrysis galbana

Journal of Agricultural and Food Chemistry, 2016
Virginia Motilva Sanchez, Elena Mª Talero Barrientos, Rodriguez-Luna Azahara   +2 more
exaly   +2 more sources