Health assessment of Galapagos pinniped pups during the 2024 El Niño event: hematological, biochemical, and morphometric findings [PDF]
Veterinary WorldBackground and Aim: The Galapagos sea lion (Zalophus wollebaeki) and Galapagos fur seal (GFS; Arctocephalus galapagoensis) are endemic pinnipeds highly vulnerable to environmental fluctuations associated with the El Niño–Southern Oscillation (ENSO). This
Eduardo A. Díaz +8 more
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Prognostic biomarkers for idiopathic pulmonary fibrosis: findings from ISABELA clinical trials [PDF]
ERJ Open ResearchBackground Idiopathic pulmonary fibrosis (IPF) is characterised by progressive loss of pulmonary function and poor survival. Although biomarkers for disease progression and mortality exist, their reliability in large studies remains unproven.
Matthew J. Randall +17 more
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Enhancing restoration success of rare plants in an arid-tropical climate through water-saving technologies: a case study of Scalesia affinis ssp. brachyloba in the Galapagos Islands [PDF]
PeerJ, 2023 Arid tropical archipelagos, such as the Galapagos Islands, host a high concentration of endemic plant species, many of which require restoration intervention to recover from past environmental degradation.
Esme Plunkett +4 more
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Species associated with whale sharks Rhincodon typus (Orectolobiformes, Rhincodontidae) in the Galapagos Archipelago [PDF]
Biodiversity Data Journal, 2023 Whale sharks Rhincodon typus frequently appear to interact or associate with other species, which vary depending on the community structure and the demographic of the whale sharks at each location globally. Here, we present the species sighted frequently
Sofia Green, Alex Hearn, Jonathan Green
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Land, 2022 Invasive species are one of the main threats to biodiversity worldwide, and the Galapagos Islands are no exception. With the need to control many invasive plant species, accurate distribution maps of invasive plant species are crucial for cost-effective ...
Carolina Carrión-Klier +4 more
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Nesting of Dark-billed Cuckoo (Coccyzus melacoryphus) on Isabela Island, Galapagos, Ecuador
El Hornero, 2023 We present new data and reviewed the information available on the breeding biology of the Dark-billed Cuckoo (Coccyzus melacoryphus), a widespread South American species.
Ibeth P. Alarcón +8 more
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High-throughput 3D microvessel-on-a-chip model to study defective angiogenesis in systemic sclerosis
Scientific Reports, 2022 In early systemic sclerosis (Scleroderma, SSc), the vasculature is impaired. Although the exact etiology of endothelial cell damage in SSc remains unclear, it is hypothesized that endothelial to mesenchymal transition (EndoMT) plays a key role.
Bart Kramer +10 more
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Development of a human primary gut-on-a-chip to model inflammatory processes
Scientific Reports, 2020 Inflammatory bowel disease (IBD) is a complex multi-factorial disease for which physiologically relevant in vitro models are lacking. Existing models are often a compromise between biological relevance and scalability.
Claudia Beaurivage +5 more
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Identification and Characterization of Novel CFTR Potentiators
Frontiers in Pharmacology, 2018 There is still a high unmet need for the treatment of most patients with cystic fibrosis (CF). The identification and development of new Cystic Fibrosis Transmembrane conductance Regulator (CFTR) modulators is necessary to achieve higher clinical benefit
Maarten Gees +15 more
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Frontiers in Pharmacology, 2019 The deletion of phenylalanine at position 508 (F508del) in cystic fibrosis transmembrane conductance regulator (CFTR) causes a severe defect in folding and trafficking of the chloride channel resulting in its absence at the plasma membrane of epithelial ...
Gert de Wilde +15 more
doaj +1 more source