Results 11 to 20 of about 19,566 (289)

Prognostic biomarkers for idiopathic pulmonary fibrosis: findings from ISABELA clinical trials [PDF]

ERJ Open Research
Background Idiopathic pulmonary fibrosis (IPF) is characterised by progressive loss of pulmonary function and poor survival. Although biomarkers for disease progression and mortality exist, their reliability in large studies remains unproven.
Matthew J. Randall, Claus A. Andersen, Kevin K. Brown, Simon de Bernard, Paul Ford, Naftali Kaminski, Michael Kreuter, Sharlene Lim, Toby M. Maher, Niyati Prasad, Antje Prasse, Philippe Pujuguet, Vincenzo Teneggi, Bernt van den Blink, Louise V. Wain, Timothy R. Watkins, Wim Wuyts, Yasmina Bauer   +17 more
doaj   +2 more sources

GALAPAGOS: From Pixels to Parameters

, 2012
To automate source detection, two-dimensional light-profile Sersic modelling and catalogue compilation in large survey applications, we introduce a new code GALAPAGOS, Galaxy Analysis over Large Areas: Parameter Assessment by GALFITting Objects from SExtractor. Based on a single setup, GALAPAGOS can process a complete set of survey images.
Barden, Marco, Häußler, Boris, Peng, Chien Y., McIntosh, Daniel H., Guo, Yicheng   +4 more
openaire   +4 more sources

Induction and Prolonged Induction With Mirikizumab in Ulcerative Colitis-A Prospective, Real-World Study From the Sicilian Network for Inflammatory Bowel Disease (SN-IBD). [PDF]

United European Gastroenterol J
ABSTRACT Background Mirikizumab (MIRI), an IgG4 monoclonal antibody targeting IL‐23 p19, was recently licensed for ulcerative colitis (UC). Most available data come from the pivotal trials, but real‐life data are scant. We aimed to evaluate the effectiveness and safety of MIRI in a real‐world setting.
Costantino G, Viola A, Iuculano A, Macaluso FS, Voti RL, Cappello M, Antoci C, Ferracane C, Sciuto M, Catarella D, Parisi S, Mocciaro F, Scrivo B, Distefano ME, Vassallo R, Minissale MG, Scalisi G, Garufi S, Rao S, Muscarella S, Tortorella V, Giangreco E, Muscianisi M, Orlando A, Fries W.   +24 more
europepmc   +2 more sources

Epidemiology, healthcare utilization, and related costs among patients with IPF: results from a German claims database analysis

Respiratory Research, 2022
Background Idiopathic pulmonary fibrosis (IPF) is a progressive form of fibrosing interstitial pneumonia with poor survival. This study provides insight into the epidemiology, cost, and disease course of IPF in Germany.
Michael Kreuter, Nils Picker, Larissa Schwarzkopf, Severin Baumann, Agustin Cerani, Roelien Postema, Ulf Maywald, Axel Dittmar, Jonathan Langley, Haridarshan Patel   +9 more
doaj   +1 more source

Galapagos Tomatoes and Tortoises [PDF]

Evolution, 1961
One of the several unique features of tomatoes native to the Galapagos IslandsLycopersicon esculentum var. minor (L. cheesmanii var. minor) and related formsis seed dormancy. Less than one per cent of their seeds, which are notably smaller than those of other known tomatoes, will germinate without treatment.
Charles M. Rick, Robert I. Bowman
openaire   +1 more source

Fog harvesting potential for domestic rural use and irrigation in San Cristobal Island, Galapagos, Ecuador

Cuadernos de Investigación Geográfica, 2020
The Galapagos Archipelago is a semiarid zone scarce of superficial water resources. Due to its geographic location and the presence of oceanic currents, these islands are covered by fog during seven months along the year which could represent a potential
P. Echeverría, Ch. Domínguez, M. Villacís, S. Violette   +3 more
doaj   +1 more source

Rewilding giant tortoises engineers plant communities at local to landscape scales

Conservation Letters, 2023
Trophic rewilding is increasingly being used to promote megafauna reintroductions to island ecosystems, yet ecosystem response to population restoration once megafauna reintroduction occurs remains understudied. In this study of a population of Galapagos
Washington Tapia Aguilera, James P. Gibbs   +1 more
doaj   +1 more source

Estimation of age and growth and mortality parameters of the sea cucumber Isostichopus fuscus (Ludwig, 1875) and implications for the management of its fishery in the Galapagos Marine Reserve

Aquaculture and Fisheries, 2020
The fishery of the sea cucumber Isostichopus fuscus was the most important one in the early 2000s in the Galapagos Marine Reserve. Its overexploitation leads to its total closure from 2016 to 2021.
Jorge Ramírez-González, Nicolas Moity, Solange Andrade-Vera, Harry Reyes Mackliff   +3 more
doaj   +1 more source

Effect of filgotinib, a selective JAK 1 inhibitor, with and without methotrexate in patients with rheumatoid arthritis: patient-reported outcomes

Arthritis Research & Therapy, 2018
Background The aim was to assess patient-reported outcomes (PROs) in patients with rheumatoid arthritis (RA) treated with filgotinib during two phase 2b, 24-week, randomized, placebo-controlled studies.
Mark Genovese, Rene Westhovens, Luc Meuleners, Annegret Van der Aa, Pille Harrison, Chantal Tasset, Arthur Kavanaugh   +6 more
doaj   +1 more source

Immune activity, body condition and human-associated environmental impacts in a wild marine mammal [PDF]

, 2013
PMB was funded by the Natural Environment Research Council (www.nerc.ac.uk), the Universities Federation for Animal Welfare (www.ufaw.org.uk) and the Sea Mammal Research Unit (www.smru.st-and.ac.uk).
Simon J Goodman, Ailsa J. Hall (29488), Patrick M Brock, Acevedo-Whitehouse, Karina, Brock, Patrick M., Goodman, Simon J., Patrick M. Brock (428558), Goodman, Simon J, Karina Acevedo-Whitehouse, Marilyn Cruz (428559), Hall, Ailsa J., Karina Acevedo-Whitehouse (408475), Ailsa J Hall, Marilyn Cruz, Simon J. Goodman (134273), Cruz, Marilyn, Brock, Patrick M, Hall, Ailsa J   +17 more
core   +1 more source