Results 21 to 30 of about 22,508 (196)

Effect of filgotinib, a selective JAK 1 inhibitor, with and without methotrexate in patients with rheumatoid arthritis: patient-reported outcomes

Arthritis Research & Therapy, 2018
Background The aim was to assess patient-reported outcomes (PROs) in patients with rheumatoid arthritis (RA) treated with filgotinib during two phase 2b, 24-week, randomized, placebo-controlled studies.
Mark Genovese, Rene Westhovens, Luc Meuleners, Annegret Van der Aa, Pille Harrison, Chantal Tasset, Arthur Kavanaugh   +6 more
doaj   +1 more source

Land Cover Classification of Complex Agroecosystems in the Non-Protected Highlands of the Galapagos Islands

Remote Sensing, 2019
The humid highlands of the Galapagos are the islands’ most biologically productive regions and a key habitat for endemic animal and plant species.
Francisco J. Laso, Fátima L. Benítez, Gonzalo Rivas-Torres, Carolina Sampedro, Javier Arce-Nazario   +4 more
doaj   +1 more source

Catch, bycatch and discards of the Galapagos Marine Reserve small-scale handline fishery [PDF]

PeerJ, 2015
Fisheries bycatch is a significant marine conservation issue as valuable fish are wasted and protected species harmed with potential negative ecological and socio-economic consequences.
Johanna S. Zimmerhackel, Anna C. Schuhbauer, Paolo Usseglio, Lena C. Heel, Pelayo Salinas-de-León   +4 more
doaj   +2 more sources

Spray-dried nanocrystal-loaded polymer microparticles for long-term release local therapies: an opportunity for poorly soluble drugs

Drug Delivery, 2023
Nano- and micro-technologies can salvage drugs with very low solubility that were doomed to pre-clinical and clinical failure. A unique design approach to develop drug nanocrystals (NCs) loaded in extended release polymeric microparticles (MPs) for local
Carlos Rodríguez-Nogales, Joke Meeus, Gaby Thonus, Sam Corveleyn, Eric Allémann, Olivier Jordan   +5 more
doaj   +1 more source

Drastic effects of El Nino on Galapagos pinnipeds [PDF]

, 1985
Trillmich F, Limberger D. Drastic effects of El Nino on Galapagos pinnipeds. Oecologia. 1985;67(1):19-22.Population dynamics of pinnipeds living in the tropical upwelling ecosystem of the Galapagos were strongly influenced by the 1982–83 Southern ...
Trillmich, Fritz ; https://orcid.org/, Limberger, Dominique   +1 more
core   +1 more source

Illegal artisanal longline use in the Galapagos Marine Reserve characterized through monitoring and control data

Frontiers in Marine Science
Illegal longline fishing in the Galapagos Marine Reserve (GMR) represents a socioecological issue with significant impact on protected marine species. This study characterizes the use of illegal longlines in the GMR by combining and analyzing datasets ...
Andres Romero-Caicedo, Paola Buitron-Lopez, Andres Tapia-Jaramillo, Simon J. McKinley, Edwin Castro-Briones, Gonzalo Sevilla-Cedeño, John Ronquillo-Garzon, Gabriel Maciel de Souza Vianna, Gabriel Maciel de Souza Vianna   +8 more
doaj   +1 more source

Characterization of proteins and fatty acid composition in galapagos fur seal milk. Occurrence of whey and casein protein polymorphisms [PDF]

, 1988
Trillmich F, Kirchmeier D, Kirchmeier O, et al. Characterization of proteins and fatty acid composition in galapagos fur seal milk. Occurrence of whey and casein protein polymorphisms.
Seewald, Markus, Kirchmeier, Otto, Seewald, M., Trillmich, Fritz ; https://orcid.org/, Trillmich, F., Scherz, H., Kirchmeier, Dorothea, Lechner, Erika, Scherz, Heimo, Lechner, E., Kirchmeier, O., Krause, I., Kirchmeier, D., Eichinger, Hans, Krause, Ingolf, Eichinger, H.   +15 more
core   +1 more source

Impact of Dual Interleukin‐17A and Interleukin‐17F Inhibition with Bimekizumab on Inflammatory and Structural Lesions in Axial Spondyloarthritis: MRI and Radiographic Outcomes from the Phase 3 BE MOBILE 1 and 2 Studies and their Open‐Label Extension

Arthritis &Rheumatology, Accepted Article.
Objectives To evaluate the impact of bimekizumab, a dual IL‐17A and IL‐17F inhibitor, on sacroiliac joint (SIJ) and spine inflammation/structural damage in axSpA using MRIs/radiographs from the phase 3 studies BE MOBILE 1 (nr‐axSpA) and 2 (r‐axSpA) and their open‐label extension (OLE).
Walter P. Maksymowych, Sofia Ramiro, Denis Poddubnyy, Xenofon Baraliakos, Robert G.W. Lambert, Ute Massow, Tom Vaux, Chetan Prajapati, Alexander Marten, Natasha de Peyrecave, Mikkel Østergaard   +10 more
wiley   +1 more source

Geographic Analysis of the Safety and Efficacy of Filgotinib in Rheumatoid Arthritis

Rheumatology and Therapy, 2022
Plain Language Summary Clinical trials in rheumatoid arthritis recruit too few patients from diverse ethnic backgrounds to be able to identify differences in treatment outcomes.
Bernard Combe, Robin Besuyen, Antonio Gómez-Centeno, Tsukasa Matsubara, Juan José Sancho Jimenez, Zhaoyu Yin, Maya H. Buch   +6 more
doaj   +1 more source

Immune activity, body condition and human-associated environmental impacts in a wild marine mammal [PDF]

, 2013
PMB was funded by the Natural Environment Research Council (www.nerc.ac.uk), the Universities Federation for Animal Welfare (www.ufaw.org.uk) and the Sea Mammal Research Unit (www.smru.st-and.ac.uk).
Simon J Goodman, Ailsa J. Hall (29488), Patrick M Brock, Acevedo-Whitehouse, Karina, Brock, Patrick M., Goodman, Simon J., Patrick M. Brock (428558), Goodman, Simon J, Karina Acevedo-Whitehouse, Marilyn Cruz (428559), Hall, Ailsa J., Karina Acevedo-Whitehouse (408475), Ailsa J Hall, Marilyn Cruz, Simon J. Goodman (134273), Cruz, Marilyn, Brock, Patrick M, Hall, Ailsa J   +17 more
core   +2 more sources