Results 21 to 30 of about 49,688 (258)
Introduction This post hoc analysis of the phase 3 rheumatoid arthritis (RA) filgotinib clinical trial program assessed the effect of filgotinib on body mass index (BMI) in patients with RA and the impact of BMI on the efficacy and safety of filgotinib ...
Alejandro Balsa +11 more
doaj +1 more source
Geographic Analysis of the Safety and Efficacy of Filgotinib in Rheumatoid Arthritis
Plain Language Summary Clinical trials in rheumatoid arthritis recruit too few patients from diverse ethnic backgrounds to be able to identify differences in treatment outcomes.
Bernard Combe +6 more
doaj +1 more source
Preliminary study of the airborne pollen in the atmosphere of Puerto Ayora (Galapagos Islands, Ecuador) [PDF]
Galapagos is an archipelago of volcanic islands located 972 km west from the continental Ecuador. They were declared by the UNESCO as a World Heritage Site and Biosphere Reserve due to their singular environmental value, where a third part of the ...
Jaramillo Díaz, Patricia +3 more
core
Romosozumab and Denosumab Combination Therapy After Denosumab in Postmenopausal Osteoporosis
Background Transition from long‐term denosumab to PTH‐analogs or romosozumab might expose patients to the risk of the so‐called rebound phenomenon. Adding romosozumab to denosumab might represent an option in patients experiencing a fracture while on denosumab.
Giovanni Adami +10 more
wiley +1 more source
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes in youth with axial juvenile spondyloarthritis (axJSpA) initiating TNF inhibitor (TNFi).
Timothy G. Brandon +8 more
wiley +1 more source
Galapagos Tomatoes and Tortoises [PDF]
One of the several unique features of tomatoes native to the Galapagos IslandsLycopersicon esculentum var. minor (L. cheesmanii var. minor) and related formsis seed dormancy. Less than one per cent of their seeds, which are notably smaller than those of other known tomatoes, will germinate without treatment.
Charles M. Rick, Robert I. Bowman
openaire +1 more source
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet +17 more
wiley +1 more source
Continuous medical and safety monitoring of subject data during a clinical trial is a critical part of evaluating the safety of trial participants and as such is governed by protocol procedures and regulatory guidelines to meet the trial's intended ...
Laure Cougnaud +7 more
doaj +1 more source
Priorities for ecological research on cetaceans in the Galápagos Islands
Located in the eastern tropical Pacific, the Galápagos Islands are an oceanic insular ecosystem subject to strong environmental variability driven by local and regional processes.
Daniel M. Palacios +3 more
doaj +1 more source

