Results 21 to 30 of about 49,790 (196)
The humid highlands of the Galapagos are the islands’ most biologically productive regions and a key habitat for endemic animal and plant species.
Francisco J. Laso +4 more
doaj +1 more source
Geographic Analysis of the Safety and Efficacy of Filgotinib in Rheumatoid Arthritis
Plain Language Summary Clinical trials in rheumatoid arthritis recruit too few patients from diverse ethnic backgrounds to be able to identify differences in treatment outcomes.
Bernard Combe +6 more
doaj +1 more source
Preliminary study of the airborne pollen in the atmosphere of Puerto Ayora (Galapagos Islands, Ecuador) [PDF]
Galapagos is an archipelago of volcanic islands located 972 km west from the continental Ecuador. They were declared by the UNESCO as a World Heritage Site and Biosphere Reserve due to their singular environmental value, where a third part of the ...
Jaramillo Díaz, Patricia +3 more
core
Continuous medical and safety monitoring of subject data during a clinical trial is a critical part of evaluating the safety of trial participants and as such is governed by protocol procedures and regulatory guidelines to meet the trial's intended ...
Laure Cougnaud +7 more
doaj +1 more source
Introduction This post hoc analysis of the phase 3 rheumatoid arthritis (RA) filgotinib clinical trial program assessed the effect of filgotinib on body mass index (BMI) in patients with RA and the impact of BMI on the efficacy and safety of filgotinib ...
Alejandro Balsa +11 more
doaj +1 more source
Galapagos Tomatoes and Tortoises [PDF]
One of the several unique features of tomatoes native to the Galapagos IslandsLycopersicon esculentum var. minor (L. cheesmanii var. minor) and related formsis seed dormancy. Less than one per cent of their seeds, which are notably smaller than those of other known tomatoes, will germinate without treatment.
Charles M. Rick, Robert I. Bowman
openaire +1 more source
Acquisition of an invasive phenotype by cancer cells is a requirement for bone metastasis. Transformed epithelial cells can switch to a motile, mesenchymal phenotype by epithelial-mesenchymal transition (EMT).
Geertje van der Horst +12 more
doaj +1 more source
Ziritaxestat, an autotaxin inhibitor, was under development for the treatment of idiopathic pulmonary fibrosis. It is a substrate of cytochrome P450 3A4 (CYP3A4) and P‐glycoprotein and a weak inhibitor of the CYP3A4 and OATP1B1 pathways.
Jeremy Perrier +5 more
doaj +1 more source

