Results 1 to 10 of about 35,897 (197)
Galectins can serve as biomarkers in COVID-19: A comprehensive systematic review and meta-analysis
BackgroundGalectins are an eleven-member class of lectins in humans that function as immune response mediators and aberrancies in their expression are commonly associated with immunological diseases.
Amir Hossein Behnoush +7 more
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“Repair Me if You Can”: Membrane Damage, Response, and Control from the Viral Perspective
Cells are constantly challenged by pathogens (bacteria, virus, and fungi), and protein aggregates or chemicals, which can provoke membrane damage at the plasma membrane or within the endo-lysosomal compartments.
Coralie F. Daussy, Harald Wodrich
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We previously observed that genomic loss of galectin‐3 (Gal‐3; encoded by Lgals3) in mice has a significant protective effect on age‐related bone loss.
Kevin A. Maupin +5 more
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Atg8ylation as a general membrane stress and remodeling response
The yeast Atg8 protein and its paralogs in mammals, mammalian Atg8s (mAtg8s), have been primarily appreciated for their participation in autophagy. However, lipidated mAtg8s, including the most frequently used autophagosomal membrane marker LC3B, are ...
Suresh Kumar, Jingyue Jia1, Vojo Deretic
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Tumor Microenvironment-Associated Extracellular Matrix Components Regulate NK Cell Function
The tumor microenvironment (TME) is composed of multiple infiltrating host cells (e.g., endothelial cells, fibroblasts, lymphocytes, and myeloid cells), extracellular matrix, and various secreted or cell membrane-presented molecules.
Gustavo Rodrigues Rossi +2 more
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Plasma Galectin-9 Concentrations in Normal and Diseased Condition
Background/Aims: Galectin-9 is a soluble immune modulator with versatile functions, including a role as an immune checkpoint molecule. Therefore, the amount of galectin-9 in the blood may reflect an individual’s immunological balance.
Toshiro Niki +6 more
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Differential Cellular Expression of Galectin-1 and Galectin-3 After Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is a devastating sub-type of stroke with no proven treatment. Given the emerging role of Galectin-1 and Galectin-3 in neuroimmune responses, the objective of the current manuscript is to elucidate hemorrhagic-injury induced
Frederick Bonsack +1 more
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N-glycosylation of membrane receptors is important for a wide variety of cellular processes. In the immune system, loss or alteration of receptor glycosylation can affect pathogen recognition, cell-cell interaction, and activation as well as migration ...
Paola de Haas +4 more
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Changes in cell growth and metabolism are affected by the surrounding environmental factors to adapt to the cell’s most appropriate growth model. However, abnormal cell metabolism is correlated with the occurrence of many diseases and is accompanied by ...
Chien-Hsiu Li +5 more
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Intrinsic tryptophan fluorescence spectroscopy reliably determines galectin-ligand interactions
Galectins are involved in the regulation of divergent physiological and pathological processes and are increasingly recognized to play important roles in a number of diseases.
Paulina Sindrewicz +5 more
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