Modulators of the Balance between M1 and M2 Macrophages during Pregnancy [PDF]
, 2017 Macrophages are a subset of mononuclear phagocytes of the innate immune system with high plasticity and heterogeneity. At the maternal–fetal interface, macrophages are present in all stages of pregnancy and involved in a variety of activities, including ...
Ai-Hua Liao +3 more
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ChemistryOpen, EarlyView.Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali +4 more
wiley +1 more source
Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1 [PDF]
, 2016 Galectin-1 (Gal-1), a glycan-binding protein with broad antiinflammatory activities, functions as a proresolving mediator in autoimmune and chronic inflammatory disorders. However, its role in allergic airway inflammation has not yet been elucidated.
Abramoff +15 more
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Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management
Rheumatology &Autoimmunity, EarlyView.Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley +1 more source
Liver eosinophilic infiltrate is a significant finding in patients with chronic hepatitis C. [PDF]
, 2008 Eosinophilic infiltrate of liver tissue is described in primary cholestatic diseases, hepatic allograft rejection and drug-induced liver injury, but its significance and its implications in chronic hepatitis C are unknown.
ALESSI, N +7 more
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Integrative Zoology, EarlyView.High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang +6 more
wiley +1 more source
Az anya immunológiai tolerancia mechanizmusai a terhesség során és azok zavarai pathológiás terhességekben: pre-eclampsiás és habituálisan vetélő betegek vizsgálata = The mechanisms of immunological tolerance during pregnancy: impaired maternal tolerance during pre-eclampsia and habitual abortion [PDF]
, 2011 Sikeres és sikertelen mesterséges megtermékenyítésen (IVF) átesett nők perifériás NK és NKT sejtjeinek fenotípusát és funkcióját vizsgáltuk. Követéses vizsgálat során a beavatkozás előtt és után nyert adatokat hasonlítottuk össze.
Barakonyi, Aliz +3 more
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CEACAM1 regulates TIM-3-mediated tolerance and exhaustion [PDF]
, 2013 T-cell immunoglobulin domain and mucin domain-3 (TIM-3, also known as HAVCR2) is an activation-induced inhibitory molecule involved in tolerance and shown to induce T-cell exhaustion in chronic viral infection and cancers[superscript 1, 2, 3, 4, 5 ...
Anderson, Ana C. +23 more
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Single‐Cell Omics Analysis of Human Basophils Reveals Two Transcriptionally Distinct Populations
Allergy, EarlyView.Integrated single‐cell transcriptomics and large‐scale immunophenotyping reveal the molecular landscape of human basophils. Circulating basophils comprise two transcriptionally distinct populations. A user‐friendly web resource enables interactive exploration of the generated data.
Sofia Papavasileiou +13 more
wiley +1 more source