Results 71 to 80 of about 4,258,326 (225)
Modulation of Animal Gut Health by Milk Oligosaccharide
Animal Research and One Health, EarlyView.This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen +7 more
wiley +1 more source
Animal lectins as cell adhesion molecules [PDF]
, 1998 Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu +2 more
wiley +1 more source
Overexpression of Galectin-9 in Islets Prolongs Grafts Survival via Downregulation of Th1 Responses
Cell Transplantation, 2013 The differential activation of T helper (Th) cells and production of cytokines contribute to graft rejection or tolerance. In general, the Th1-type cytokines and cytotoxic T-cells are detected consistently in a host who is undergoing rejection, whereas ...
Feng-Cheng Chou +6 more
doaj +1 more source
From Interferon Signature to the Clinical Landscape: Type I Interferonopathies
Arthritis &Rheumatology, Accepted Article.Background Type I interferonopathies are heterogeneous diseases driven by dysregulated IFN‐I signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. Objective To characterize the clinical, immunological, genetic, molecular profiles of patients with suspected enhanced IFN‐I signaling, and assess ...
Ismail Yaz +13 more
wiley +1 more source
BMEMat, EarlyView.This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam +4 more
wiley +1 more source
Brain and BehaviorPurpose The number of studies conducted on the role of neuroinflammation in the etiopathogenesis of bipolar disorder has been increasing in recent years.
Elcicek Selahaddin +6 more
doaj +1 more source
Peripheral blood TIM-3 positive NK and CD8+ T cells throughout pregnancy: TIM-3/galectin-9 interaction and its possible role during pregnancy. [PDF]
PLoS ONE, 2014 The T-cell immunoglobulin and mucin domain (TIM) family is a relatively newly described group of molecules with a conserved structure and important immunological functions. Identification of Galectin-9 as a ligand for TIM-3 has established the Galectin-9/
Matyas Meggyes +6 more
doaj +1 more source
Galectin-3 promotes EV71 infection.
, 2016 (A) Using TALEN, ablation of the galectin-3 gene was performed in RD cells. Two clones of galectin-3 knock-out (G3KO) RD cells were selected. Protein expression of galectin-3 was examined in cell lysates from RD cells and two G3KO clones (G3KO-A1 and ...
Yungling Lee (3454598) +7 more
core +1 more source
Quantitative Expression of C-Type Lectin Receptors in Humans and Mice [PDF]
, 2012 C-type lectin receptors, their adaptor molecules and S-type lectins (galectins) are involved in the recognition of glycosylated self-antigens and pathogens.
Lech, Maciej +12 more
core +1 more source