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Galectin-1 Purified from Human Platelets.
Blood, 2005Abstract Galectins are a family of lectins which exhibit β-galactoside-binding activity. They are Ca++-independent and have a common consensus sequence in the carbohydrate binding domain. Fourteen mammalian members of this family have been sequenced and well-characterised in different species, although galectins-1 and -3 have been the ...
Mariana M. Gonzalez, Nilda Ester Fink
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Galectin-1: Forms and Functions
2012Galectin-1 (Gal-1) is an animal lectin ranging from Caenorhabditis elegans to humans, which is defined by the affinity for β-galactosides and by significant sequence similarity in carbohydrate-binding site. Gal-1 is differentially expressed by various normal and pathological tissues and appears to be functionally polyvalent, with a wide range of ...
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Immunomodulatory drugs affect galectin-1 expression
2007Galectin-1, a β -galactoside binding lectin, a well known regulator of T-cell homeostasis and survival, was recently shown to be also involved in control of monocyte/macrophage physiology. While galectin-1 mainly acts as an anti-inflammatory molecule, another member of galectin family, galectin-3 is known as a strong pro-inflammatory signal.
Dumić, J, Šupraha, S, Dabelić, S
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Galectin-1 in injury and regeneration
2004In higher vertebrates, injury to both sensory and motor axons within the central nervous system (CNS) results in permanent loss of sensation and paralysis. In contrast, peripheral nervous system (PNS) injuries are often followed by functional recovery.
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