Results 41 to 50 of about 43,144 (243)
Galectinology of Equine Pregnancy
Animals, 2022 Galectins are a family of proteins that bind to glycans, acting in a cytokine-like manner throughout the body. In the majority of mammalians, galectins have been found to be involved in pregnancy maintenance, but few studies have evaluated this in the ...
Carleigh E. Fedorka +2 more
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Galectin-1 is essential for efficient liver regeneration following hepatectomy [PDF]
, 2016 Galectin-1 (Gal1) is a known immune/inflammatory regulator which actsboth extracellularly and intracellularly, modulating innate and adaptive immuneresponses. Here, we explored the role of Gal1 in liver regeneration using 70% partial hepatectomy (PHx) of
Cerliani, Juan Pablo +7 more
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Human T cell glycosylation and implications on immune therapy for cancer [PDF]
, 2020 Glycosylation is an important post-translational modification, giving rise to a diverse and abundant repertoire of glycans on the cell surface, collectively known as the glycome.
Callewaert, Nico +3 more
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Бюллетень сибирской медицины, 2020 The aim of the study was to characterize the features of the subpopulation composition and cytokine-secretory activity of T lymphocytes (Th1, Th17 and Treg) in relation to the concentration of galectin-1 and galectin-3 in the blood of patients with colon
V. S. Poletika +8 more
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Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin [PDF]
, 2002 The squamous stratified epithelia contain a proliferative (harboring mitotic activity) and a differentiating compartment. Due to the potential of protein-carbohyd rate interactions to regulate cellular activities we introduced a mammalian lectin to cyto-
Dvorankova, Barbora +7 more
core +1 more source
“Supra”molecular Recognition of Galectin 1
Chemistry & Biology, 2007 In this issue of Chemistry & Biology, Belitsky et al. [1] elegantly describe the use of supramolecular complexes of sugars to multivalently target Galectin-1 (Gal-1), a lectin involved in the organization of cell surface glycoproteins, signaling, cell death, and cancer metastasis.
Disney, Matthew D. +1 more
openaire +2 more sources
Galectin-1 links tumor hypoxia and radiotherapy [PDF]
Glycobiology, 2014 Radiation therapy is a main stay in treating solid tumors and plays a significant role in definitive and adjuvant therapy. Unfortunately, local control remains a challenge, in which the success of radiotherapy is largely dictated by tumor hypoxia, DNA damage repair and the antitumor immune response.
Peiwen, Kuo, Quynh-Thu, Le
openaire +2 more sources
Frontiers in Immunology, 2017 Many infectious diseases are characterized by the development of immunoregulatory pathways that contribute to pathogen persistence and associated disease symptoms.
Patrick T. Bunn +15 more
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Galectin-1 as a predictive biomarker in ovarian cancer
Journal of Ovarian Research, 2021 Aim There is an urgent need to set up a useful biomarker for ovarian cancer. Galectin-1 is a promising carbohydrate-binding protein which plays a remarkable role in various malignancies yet its clinical significance is questionable.
Mahak Masoodi +8 more
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Enhanced Susceptibility of Galectin-1 Deficient Mice to Experimental Colitis
Frontiers in Immunology, 2021 Galectin-1 is a β-galactoside-binding lectin, ubiquitously expressed in stromal, epithelial, and different subsets of immune cells. Galectin-1 is the prototype member of the galectin family which shares specificity with β-galactoside containing proteins ...
Raquel Fernandez-Perez +13 more
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