Results 21 to 30 of about 113,439,941 (280)

Human Galectins Induce Conversion of Dermal Fibroblasts into Myofibroblasts and Production of Extracellular Matrix: Potential Application in Tissue Engineering and Wound Repair [PDF]

open access: yes, 2011
Members of the galectin family of endogenous lectins are potent adhesion/growth-regulatory effectors. Their multi-functionality opens possibilities for their use in bioapplications. We studied whether human galectins induce the conversion of human dermal
Lacina, Lukas   +21 more
core   +1 more source

Differential Cellular Expression of Galectin-1 and Galectin-3 After Intracerebral Hemorrhage

open access: yesFrontiers in Cellular Neuroscience, 2019
Intracerebral hemorrhage (ICH) is a devastating sub-type of stroke with no proven treatment. Given the emerging role of Galectin-1 and Galectin-3 in neuroimmune responses, the objective of the current manuscript is to elucidate hemorrhagic-injury induced
Frederick Bonsack   +1 more
doaj   +1 more source

Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer [PDF]

open access: yes, 2005
Objective: To determine the expression of endogenous adhesion/growth-regulatory lectins and their binding sites using labeled tissue lectins as well as the binding profile of hyaluronic acid as an approach to define new prognostic markers.
Szöke, Tamas   +9 more
core   +1 more source

Galectin-1 and Galectin-3 expression in colon cancer and its correlation with tumor invasion, differentiation, and metastatic spread

open access: yesФундаментальная и клиническая медицина, 2021
Aim. To study the expression of galectin-1 and galectin-3 in colon cancer and the levels of these proteins in the peripheral blood in relation to the differentiation, invasion, and metastatic dissemination.Materials and Methods.
Yu. V. Kolobovnikova   +8 more
doaj   +1 more source

Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection. [PDF]

open access: yes, 2012
The S-type lectin galectin-9 binds to the negative regulatory molecule Tim-3 on T cells and induces their apoptotic deletion or functional inactivation.
Cheng, Y   +59 more
core   +1 more source

Galectin-3 facilitates cell motility in gastric cancer by up-regulating protease-activated receptor-1 (PAR-1) and matrix metalloproteinase-1 (MMP-1).

open access: yesPLoS ONE, 2011
BackgroundGalectin-3 is known to regulate cancer metastasis. However, the underlying mechanism has not been defined. Through the DNA microarray studies after galectin-3 silencing, we demonstrated here that galectin-3 plays a key role in up-regulating the
Seok-Jun Kim   +6 more
doaj   +1 more source

Galectins and Their Ligand Glycoconjugates in the Central Nervous System Under Physiological and Pathological Conditions

open access: yesFrontiers in Neuroanatomy, 2021
Galectins are β-galactoside-binding lectins consisting of 15 members in mammals. Galectin-1,-3,-4,-8, and -9 are predominantly expressed in the central nervous system (CNS) and regulate various physiological and pathological events.
Junko Nio-Kobayashi, Tetsuya Itabashi
doaj   +1 more source

Evaluation of Plasma Concentrations of Galectins-1, 2 and 12 in Psoriasis and Their Clinical Implications

open access: yesBiomolecules, 2023
Psoriasis is a complex disease that nowadays is considered not only a dermatosis but a kind of systemic disorder associated with many accompanying diseases. Metabolic complications leading to cardiovascular incidences are the cause of increased mortality
Julia Nowowiejska   +5 more
doaj   +1 more source

Galectin-1 in myelin repair

open access: yesOncotarget, 2016
Fil: Pasquini, Laura Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica.
Rinaldi, Mariana   +2 more
openaire   +3 more sources

Galectins-1 and-3 Increase in Equine Post-traumatic Osteoarthritis

open access: yesFrontiers in Veterinary Science, 2018
Galectins are potent regulators of cell adhesion, growth and apoptosis in diverse cell types, including chondrocytes and synovial fibroblasts. Elevations in synovial fluid galectin-3 have been observed in rheumatoid arthritis, juvenile idiopathic ...
Heidi L. Reesink   +7 more
doaj   +1 more source

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