Results 31 to 40 of about 21,276,578 (296)
Galectin-1 promotes gastric cancer peritoneal metastasis through peritoneal fibrosis
BMC Cancer, 2023 Background Peritoneal metastasis is one of the main causes of death in patients with gastric cancer (GC). Galectin-1 regulates various undesirable biological behaviors in GC and may be key in GC peritoneal metastasis. Methods In this study, we elucidated
Xianhe Shen +8 more
doaj +1 more source
Biomolecules, 2023 Psoriasis is a complex disease that nowadays is considered not only a dermatosis but a kind of systemic disorder associated with many accompanying diseases. Metabolic complications leading to cardiovascular incidences are the cause of increased mortality
Julia Nowowiejska +5 more
doaj +1 more source
Monovalent Interactions of Galectin-1
Biochemistry, 2010 Galectin-1, a β-galactoside binding lectin involved in immunoregulation and cancer, binds natural and many synthetic multivalent glycoconjugates with an apparent glycoside cluster effect, that is, affinity above and beyond what would be expected from the concentration of the determinant sugar. Here we have analyzed the mechanism of such cluster effects
Emma, Salomonsson +11 more
openaire +2 more sources
Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]
, 1998 Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Korabiowska, M. +3 more
core +1 more source
The role of galectin-1 in type 2 diabetes. Clinical and experimental studies [PDF]
, 2022 Aim: The purpose of this thesis was to identify a new agent in the subcutaneous adipose tissue and assess its clinical potential in the context of type 2 diabetes.
Fryk, Emanuel
core +1 more source
Glycodendrimers: tools to explore multivalent galectin-1 interactions
Beilstein Journal of Organic Chemistry, 2015 Four generations of lactose-functionalized polyamidoamine (PAMAM) were employed to further the understanding of multivalent galectin-1 mediated interactions.
Jonathan M. Cousin, Mary J. Cloninger
doaj +1 more source
Galectins-1 and-3 Increase in Equine Post-traumatic Osteoarthritis
Frontiers in Veterinary Science, 2018 Galectins are potent regulators of cell adhesion, growth and apoptosis in diverse cell types, including chondrocytes and synovial fibroblasts. Elevations in synovial fluid galectin-3 have been observed in rheumatoid arthritis, juvenile idiopathic ...
Heidi L. Reesink +7 more
doaj +1 more source
Galectin-1 and -9 in angiogenesis: A sweet couple [PDF]
Glycobiology, 2014 The growth of new blood vessels out of the pre-existing vasculature, i.e., angiogenesis, is executed by endothelial cells that normally form the inner lining of blood vessels. During angiogenesis, these cells exert different activities which require interactions with other cells and with the extracellular environment.
Thijssen, V.L.J.L., Griffioen, A.W.
openaire +2 more sources
NAFLD‐related hepatocellular carcinoma: The growing challenge
Hepatology, EarlyView., 2022 Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah +2 more
wiley +1 more source
Cellular Physiology and Biochemistry, 2018 Background/Aims: Immune tolerance is considered the only way to manage liver transplantation (LT). The current study hypothesized that galectin-1 via the activation of hepatic stellate cells (HSCs) is capable of inducing immune tolerance in LT.
Zhi-Jun Jiang +5 more
doaj +1 more source