Results 41 to 50 of about 21,276,578 (296)
Hepatology, EarlyView., 2022 IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu +20 more
wiley +1 more source
Galectinology of Equine Pregnancy
Animals, 2022 Galectins are a family of proteins that bind to glycans, acting in a cytokine-like manner throughout the body. In the majority of mammalians, galectins have been found to be involved in pregnancy maintenance, but few studies have evaluated this in the ...
Carleigh E. Fedorka +2 more
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Бюллетень сибирской медицины, 2020 The aim of the study was to characterize the features of the subpopulation composition and cytokine-secretory activity of T lymphocytes (Th1, Th17 and Treg) in relation to the concentration of galectin-1 and galectin-3 in the blood of patients with colon
V. S. Poletika +8 more
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Galectin-1 Pulls the Strings on VEGFR2 [PDF]
Cell, 2014 Anti-vascular endothelial growth factor (VEGF) cancer immunotherapy targets angiogenesis but development of resistance in patients is common. In this issue of Cell, Croci et al. identify a complex set of mechanisms by which galectin-1 prolongs cell-surface retention of VEGF receptor 2 (VEGFR2) and stimulates VEGF-independent tumor angiogenesis.
openaire +2 more sources
Frontiers in Immunology, 2017 Many infectious diseases are characterized by the development of immunoregulatory pathways that contribute to pathogen persistence and associated disease symptoms.
Patrick T. Bunn +15 more
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Enhanced Susceptibility of Galectin-1 Deficient Mice to Experimental Colitis
Frontiers in Immunology, 2021 Galectin-1 is a β-galactoside-binding lectin, ubiquitously expressed in stromal, epithelial, and different subsets of immune cells. Galectin-1 is the prototype member of the galectin family which shares specificity with β-galactoside containing proteins ...
Raquel Fernandez-Perez +13 more
doaj +1 more source
PLoS ONE, 2011 Sera from 25 metastatic breast cancer patients and 25 healthy controls were subjected to affinity chromatography using immobilized galectin-1. Serum from the healthy subjects contained on average 1.2 mg per ml (range 0.7-2.2) galectin-1 binding ...
Michael C Carlsson +11 more
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“Supra”molecular Recognition of Galectin 1
Chemistry & Biology, 2007 In this issue of Chemistry & Biology, Belitsky et al. [1] elegantly describe the use of supramolecular complexes of sugars to multivalently target Galectin-1 (Gal-1), a lectin involved in the organization of cell surface glycoproteins, signaling, cell death, and cancer metastasis.
Disney, Matthew D. +1 more
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Animal lectins as cell adhesion molecules [PDF]
, 1998 Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
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Frontiers in Microbiology, 2022 Trypanosoma cruzi, the protozoan parasite causative agent of Chagas disease, affects about seven million people worldwide, representing a major global public health concern with relevant socioeconomic consequences, particularly in developing countries ...
Carolina V. Poncini +5 more
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